支气管黏液表皮样癌^(18)F-FDG PET/CT表现  

^(18)F-FDG PET/CT manifestations of bronchial mucoepidermoid carcinoma

作　　者：张银 汤泊 李天女[2] 丁重阳[2] ZHANG Yin;TANG Bo;LI Tiannyu;DING Chongyang(Department of Radiology,Shuyang Affilicated Hospital of Nanjing University of Chinese Medicine,Shuyang 223600,China;Department of Nuclear Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京中医药大学沭阳附属医院放射科,江苏沭阳223600 [2]南京医科大学第一附属医院核医学科,江苏南京210029

出　　处：《中国医学影像技术》2018年第9期1360-1363,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨支气管黏液表皮样癌(BMEC)的^(18)F-FDGPET/CT表现。方法回顾性分析经病理证实的8例BMEC患者的临床及^(18)F-FDGPET/CT资料,观察肿瘤的生长部位、形态、大小、密度、边缘等,测量肿瘤最大标准摄取值(SUVmax),并分析其与肿瘤大小的相关性。结果 8例BMEC肿瘤发生于主支气管1例,叶支气管2例,段支气管5例;肿瘤边缘均光滑,肿瘤形态为分叶状2例,圆形或椭圆形6例;6例病灶密度与胸壁肌肉密度相仿,1例病灶密度低于胸壁肌肉密度,1例表现为高密度钙化结节;1例伴淋巴结转移及右侧肾上腺转移,其余7例均未发现淋巴结及远处转移。8例原发灶SUVmax为5.27±4.17,肿瘤最大径为(29.46±17.33)mm;肿瘤大小与SUVmax呈正相关(r=0.958,P<0.001)。6例低级别BMEC病灶SUVmax为3.37±1.26,2例高级别分别为14.63、7.34,二者差异有统计学意义(Z=-2.000,P=0.046)。结论 BMEC好发于叶或段支气管,^(18)F-FDGPET/CT多表现为边缘光滑的类圆形软组织结节或肿块,肿瘤越大、恶性程度越高,则18F-FDG摄取越高。Objective To assess 18 F-FDG PET/CT characteristics of bronchial mucoepidermoid carcinoma(BMEC).Methods Clinical data and 18 F-FDG PET/CT imaging findings of 8 patients with BMEC proved by pathology were analyzed retrospectively.The location,shape,size,density and edge of tumors were observed,respectively.The maximum standardized uptake value(SUV max)of BMEC lesions was measured,and the correlation between SUV max and tumor size was analyzed.Results Among 8 BMEC lesions,1 tumor located in main bronchi,2 located in lobar bronchus and 5 in segmental bronchus.All lesions had smooth edge,whereas 2 were lobular,6 were oval or round shaped.The density of 6 lesions was similar to chest wall muscles,1 was lower than the muscles and 1 manifested as a calcified nodule.Multiple lymphatic and right adrenal metastasis were detected in 1 patient,while no lymphatic nor distal metastasis was found in the other 7 patients.The maximum diameter of tumor was(29.46±17.33)mm,SUV max was 5.27±4.17,and there was positive correlation between them(r=0.958,P<0.001).SUV max of 6 low-grade BMEC was 3.37±1.26,of 2 high-grade BMEC was 14.63 and 7.34,respectively,and the difference was statistically significant(Z=-2.000,P=0.046).Conclusion BMEC usually locates in lobar and segmental bronchus with smooth edge and round-like shape on 18 F-FDG PET/CT imaging.High 18 F-FDG uptake strongly correlates with poor differentiation and large tumor size of BMEC.

关 键 词：呼吸道肿瘤 癌 黏液表皮样 体层摄影术 X线计算机 体层摄影术 发射型计算机 氟脱氧葡萄糖F18 

分 类 号：R734.1[医药卫生—肿瘤] R817.4[医药卫生—临床医学]