以截瘫为临床表现的弥漫性大B细胞淋巴瘤合并甲状腺肿瘤一例  

A case report of diffuse large B-cell lymphoma combined with thyroid neoplasms with paraplegia as the clinical manifestation

作　　者：曹秋颖 牛海玥 齐薇薇[1] 王一浩[1] 江汇娟[1] 王化泉[1] 邵宗鸿[1] CAO Qiu-ying;NIU Hai-yue;QI Wei-wei;WANG Yi-hao;JIANG Hui-juan;WANG Hua-quan;SHAO Zong-hong(Department of Hematology,Tianjin Medical University General Hospital,Tianjin 300052,China)

机构地区：[1]天津医科大学总医院血液科,300052

出　　处：《天津医药》2018年第8期824-827,共4页Tianjin Medical Journal

基　　金：国家自然科学基金资助项目(81370607;81170472;81700117;81400088)

摘　　要：弥漫性大B细胞淋巴瘤(DLBCL)是非霍奇金淋巴瘤(NHL)中最常见的一个亚型,发病年龄范围宽,在临床特征、侵袭部位、组织形态学、分子遗传学、免疫表型等方面均表现出明显的异质性。此外,随着恶性肿瘤诊治水平的提高,同一患者存在多原发性恶性肿瘤(MPMT)的报道呈上升趋势。本文报告我科收治的以截瘫为临床表现的DLBCL合并甲状腺肿瘤1例。Diffuse large B-cell lymphoma(DLBCL)is the most common subtype of non-hodgkin’s lymphoma(NHL),which has a wide range in age of onset,and has obvious heterogeneity in clinical features,invasive areas,histomorphology,molecular genetics and immune phenotype.In addition,with the improvement of the diagnosis and treatment of malignant tumor,the report of multiple primary malignant tumors(MPMT)in the same patient is on the rise.This paper reports a case of DLBCL combined with thyroid neoplasms with paraplegia as the clinical manifestation.

关 键 词：截瘫 淋巴瘤 大B细胞 弥漫性 原发性骨淋巴瘤 多原发性恶性肿瘤 

分 类 号：R733.41[医药卫生—肿瘤]