胃癌术中植入氟安的临床观察  

Clinical Observation of Intraoperative Implantation of Fluoride in Gastric Cancer

作　　者：宋财立 礼巍[1] 徐志强[1] 江洋深[1] SONG Cai-li;LI Wei;XU Zhi-qiang;WANG Yang-shen(Department of General Surgery,Affiliated Xinhua Hospital of Dalian University,Dalian 116021,China)

机构地区：[1]大连大学附属新华医院普外科,辽宁大连116021

出　　处：《中国医药指南》2018年第22期24-25,共2页Guide of China Medicine

摘　　要：目的探讨胃癌患者术中植入氟安的临床有效性和安全性。方法收集2015年1月至2016年1月我院普外科接受胃癌手术的患者70例,采用信封法随机分为试验组与对照组。试验组35例采用术中植入氟安,对照组35例采用空白对照。观察术后两组患者白细胞计数和术后并发生发生率和1年生存率和转移率。结果术后空白对照组和试验组患者的白细胞计数、并发生发生率和1年生存率比较差异没有统计学意义(P>0.05)。1年转移率比较差异具有统计学意义(P<0.05)。结论胃癌患者术中植入氟安安全可靠,可以降低1年转移率,可以应用于临床。Objective To investigate the clinical efficacy and safety of intraoperative safety of fluoride in patients with gastric cancer.Methods From January 2015 to January 2016,70 cases of gastric cancer surgery in department of general surgery of our hospital were randomly divided into the experimental group and the control group.The experimental group 35 cases,the use of intraoperative fluoride safety.The control group 35 cases,using blank control.The white blood cell count,postoperative morbidity and 1 year survival rate and metastasis rate were observed in the two groups.Results There was no significant difference in white blood cell count,incidence and 1-year survival rate between the blank control group and the experimental group(P>0.05).The 1 year metastasis rate of the experimental group was lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion The results showed that the safety of fluoride implantation in patients with gastric cancer was safe and reliable,and it can reduce the metastasis rate in 1 years,and can be applied to the clinical practice.

关 键 词：胃癌 氟尿嘧啶植入 安全性 1年转移率 

分 类 号：R735.2[医药卫生—肿瘤]