艾蒿油-壳聚糖抗菌微胶囊的制备及其应用  

Preparation and application of antimicrobial mug wort oil-chitosan microcapsules

作　　者：王亚 黄菁菁[2] 张如全[2] WANG Ya;HUANG Jingjing;ZHANG Ruquan(College of Clothing Technology,Wuhan Textile University,Wuhan,Hubei 430073,China;Key Laboratory of Textile Fiber&Product,Ministry of Education,Wuhan Textile University,Wuhan,Hubei 430073,China)

机构地区：[1]武汉纺织大学服装学院,湖北武汉430073 [2]武汉纺织大学纺织纤维及制品教育部重点实验室,湖北武汉430073

出　　处：《纺织学报》2018年第10期99-103,共5页Journal of Textile Research

基　　金：湖北省自然科学基金重点项目(2013CFA090)

摘　　要：为研制用于医用非织造布抗菌整理的低毒高效广谱的天然抗菌剂,采用乳化交联法,制备艾蒿油-壳聚糖抗菌微胶囊。研究了艾蒿油与壳聚糖质量比、水相与油相的体积比、复乳搅拌速度对微胶囊的外观形态及尺寸的影响;借助扫描电子显微镜、傅里叶红外光谱仪、马尔文粒度分析仪等对样品进行表征;将抗菌微胶囊用于医用非织造布的整理并测试其抗菌性能。结果表明:艾蒿油与壳聚糖的质量比为2∶1,水相与油相的体积比为1∶5,搅拌速度为800 r/min为最佳制备条件,制得的微胶囊尺寸分布在800～1 800 nm之间,均匀度好;当微胶囊质量浓度为20 g/L,表面活性剂质量浓度为2.0 g/L,2D树脂质量浓度为120 g/L,氯化镁质量浓度为28 g/L,热烘温度为50℃,整理试样对金黄色葡萄球菌和大肠杆菌的抑菌率分别为96.66%和98.88%。In order to develop a kind of low toxicity,high efficiency and broad spectrum natural antimicrobial agent ued for antimicrobial finishing of medical nonwovens,the antimicrobial mug wort oil-chitosan microcapsules were prepared by emulsion crosslinking.The effect of mass ratio of mug wort oilto chitosan,volume ratio of water continuous phase to oilouter phase,speed of stirring on the appearance morphology and size of the microcapsules was investigated.The microcapsules were characterized by scanning electron microscopy,Fourier tansfer infrared red and a laser particle size analyzer.The results show that the optimal conditions are mass ratio of mug wort oilto chitosan of 2∶1,volume ratio of water continuous phase to oilouter phase of 1∶5,and the stirring speed of 800 r/min.The size of microcapsules is 800-1 800 nm,and the particle size distribution is narrow.When the mass concentrations of the microcapsules,the surfactant,2D resin and magnesium chloride are 20 g/L,2.0 g/L,120 g/L and 28 g/L,respectively,and the drying temperature is 50℃.The finished samples show the antibacterial rate of Staphylococcus aureus and Escherichia coli reaches 96.66%and 98.88%,respectively.

关 键 词：壳聚糖微胶囊 抗菌整理 乳化化学交联法 非织造布 天然抗菌剂 

分 类 号：TS195[轻工技术与工程—纺织化学与染整工程] TS176[轻工技术与工程—纺织科学与工程]