33例军队吉兰-巴雷综合征患者临床特点及防治研究  

Ananlysis of clinical characteristics,prevention and treatment of 33 cases of army with Guillain-Barre syndrome

作　　者：王雪笠[1] 朱艳霞[1] 余鹏霄 王丽[1] 周毅[1] 李波[1] 高利涛[1] WANG Xue-li;ZHU Yan-xia;YU Peng-xiao;WANG Li;ZHOU Yi;LI Bo;GAO Li-tao(Department of Neurology,Bethune International Peace Hospital of PLA,Shijiazhuang 050082,China)

机构地区：[1]解放军白求恩国际和平医院神经内科,河北石家庄050082

出　　处：《临床军医杂志》2018年第10期1223-1225,共3页Clinical Journal of Medical Officers

摘　　要：目的分析军人吉兰-巴雷综合征患者的发病特征及临床表现,探讨吉兰-巴雷综合征预防与治疗方法。方法回顾性分析1984—2017年收治的322例吉兰-巴雷综合征患者临床资料,其中,289例非军人患者为A组,33例军人患者为B组。观察并比较两组患者发病年龄、发病季节、发病前诱因、就诊时间及临床表现的特征,以及患者预后情况。结果两组同年龄段患者比例比较,差异有统计学意义(P <0. 05)。A组患者发病季节主要为夏季,其余依次为春季、秋季及冬季,其中,春季、夏季、秋季发病患者比例高于冬季,春季、夏季高于秋季,差异有统计学意义(P <0. 05)。B组患者发病季节主要为春季,其余依次为秋季、夏季及冬季,其中,春季、夏季、秋季发病患者比例高于冬季,春季、秋季高于夏季,差异有统计学意义(P <0. 05)。两组患者发病季节分布比较,差异无统计学意义(P> 0. 05)。B组患者发病至住院时间为(3. 58±5. 32) d短于A组的(7. 08±9. 69) d,组间比较,差异有统计学意义(P <0. 05)。发病前诱因及前驱症状方面,A组患者主要为呼吸道感染症状、腹泻病史,B组患者主要为呼吸道感染症状,两组患者均存在的主要发病诱因分布比较,差异有统计学意义(P <0. 05)。B组患者预后优于A组,两组比较,差异有统计学意义(P <0. 05)。结论吉兰-巴雷综合征临床表现多样,但有一定的规律,应积极预防、早期诊断,尽早治疗,以减少吉兰-巴雷综合征患病率、残疾率及病死率。Objective To investigate the disease characteristics and clinical manifestation of military patients with Guillain-Barre syndrome(GBS),and to prevent and treat GBS actively in order to reduce the prevalence,disability rate and mortality of GBS in military.Methods A retrospective study was performed on 322 cases of GBS patients who were admitted from 1984 to 2017.Among the patients,289 cases of non servicemen were divided into the Group A,33 cases of servicemen were divided into the Group B.To observe the characteristics of patients with GBS in the age of onset,onset season,inducement before onset,time of visit,and clinical manifestation different from those of non servicemen.Results The proportion of patients of the same age group was compared between the two groups,and the difference was statistically significant(P<0.05).The incidence season of patients in Group A was mainly summer,followed by spring,autumn and winter,among which the incidence rate of patients in spring,summer and autumn was higher than that in winter and that in spring and summer was higher than that in autumn,with statistically significant differences(P<0.05).The incidence season of patients in Group B was mainly spring,followed by autumn,summer and winter,among which the incidence rate of patients in spring,summer and autumn was higher than that in winter,and that in spring and autumn was higher than that in summer(P<0.05).The difference between the two groups was not statistically significant(P>0.05).The time between onset and hospitalization of the patients in Group A[(7.08±9.69)days]was higher than that in Group B[(3.58±5.32)days],and the difference was statistically significant(P<0.05).Premorbid inducement and prodrome symptoms,patients in Group A were mainly respiratory tract infection symptoms and diarrhea history,and patients in Group B were mainly respiratory tract infection symptoms.The distribution of major precursors in both groups was compared,and the difference was statistically significant(P<0.05).The prognosis of patients in

关 键 词：吉兰-巴雷综合征 军人 发病特征 预防 

分 类 号：R745.43[医药卫生—神经病学与精神病学]