NRS 2002与PG-SGA在肿瘤患者中的应用和比较  

Nutritional assessment in oncology patients: a comparative analysis between NRS 2002 and PG-SGA

作　　者：龚丽青[1] 刘妮[1] 王艳莉[1] 辛晓伟[1] 宗祥龙[1] 孙艳[1] 姜蕾蕾[1] 张小田[1] 岳海振[1] 方玉[1] GONG Li-qing;LIU Ni;WANG Yan-li;XIN Xiao-wei;ZONG Xiang-long;SUN Yan;JIANG Lei-lei;ZHANG Xiao-tian;YUE Haizhen;FANG Yu(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education),Department of Nutritional,Peking University Cancer Hospital&Institute,Beijing 100142,China)

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所营养科,恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142

出　　处：《肿瘤代谢与营养电子杂志》2018年第2期151-154,共4页Electronic Journal of Metabolism and Nutrition of Cancer

基　　金：北京市自然科学基金(1174016,7172048,1184014);首都卫生发展科研专项(首发2018-4-1027)

摘　　要：目的明确NRS 2002和PG-SGA对住院肿瘤患者进行营养风险筛查与评估的适用性。方法对2015年2月至4月在我院采用不同治疗方式进行治疗的肿瘤患者进行横断面调查研究,每名患者同时采用NRS 2002量表及PG-SGA量表进行营养筛查及评估,比较两种方法间的相关性及灵敏度、特异度、阳性及阴性预测值等指标。结果共423例患者完成调查,其中胃肠外科124例、放疗科169例、消化内科130例;胃肠肿瘤265例(62.6%),头颈肿瘤93例(21.9%),其他部位肿瘤65例(15.4%)。根据BMI评价,消瘦患者占9.5%;根据NRS 2002评分,有营养风险患者占32.6%;根据PG-SGA评价,中重度营养不良患者占50.6%。采用二分类交叉列表方式评价两种工具的一致性,具有一致性(kappa=0.491,P<0.001)。如果以NRS 2002≥3分作为有营养风险的评估标准,PG-SGA≥4分作为阳性对照,则NRS 2002的灵敏度为57.0%,特异度为92.3%。结论 NRS 2002用于筛查肿瘤患者的营养状况与PG-SGA的评估结果存在一致性。如果以PG-SGA≥4分作为阳性对照,NRS 2002的特异度及阳性预测值比较好,灵敏度及阴性预测值较差。Objective To investigate the applicability of NRS 2002 and PG-SGA in screening nutritional risks in tumor inpatients.Methods We carried on the cross-sectional investigation in the cancer inpatients with different therapy methods,from February 2015 to April 2015.NRS 2002 and PG-SGA were both used for nutritional screening and evaluation,comparing the correlation sensitivity,specific,positive and negative predictive value.Results A total of 423 patients completed the study,including 124 from gastrointestinal surgery,169 from radiotherapy and 130 from gastrointestinal oncology.There were 265(62.6%)cases of gastrointestinal tumor,93(21.9%)cases of head and neck tumor,65(15.4%)cases of other tumors.According to BMI,9.5%of the participants were underweight.According to NRS 2002,32.6%of the participants had nutritional risk;according to PGSGA,moderate and severe malnutriton accounted for 50.6%.Besides,NRS 2002 and PG-SGA had certain agreement by binary classification of cross(kappa=0.491,P<0.001).If we use NRS2002≥3 as nutritional risk assessment criterion,PG-SGA≥4 as positive control,the sensitivity and specificity of NRS 2002 were 57.0%and 92.3%,respectively.Conclusions The study indicated that NRS 2002 using for screening the nutritional risk and PG-SGA had certain agreement for cancer patients.If the PG-SGA≥4 was used as the positive control,the specificity and positive predictive value of NRS 2002 were better,but the sensitivity and negative predictive value were poor.

关 键 词：NRS2002 PG-SGA 消化道肿瘤 营养状况 

分 类 号：R730.5[医药卫生—肿瘤]