胎盘多肽对于肺癌术后患者免疫功能的影响及药理研究  

Effect of Placental Polypeptide on Immune Function of Patients after Lung Cancer Surgery and Pharmacological Study

作　　者：王妍[1] WANG Yan(Department of Pharmacy,Dalian Friendship Hospital,Dalian 116001,China)

机构地区：[1]大连市友谊医院药剂科,辽宁大连116001

出　　处：《中国医药指南》2018年第29期15-16,共2页Guide of China Medicine

摘　　要：目的探讨胎盘多肽应用于肺癌术后患者的临床疗效观察级药理研究。方法选取自2016年5月至2017年5月于大连市友谊医院关节接受肺癌术后化疗的患者60例,通过随机信封法分为对照组30例,应用吉西他滨联合顺铂方案化疗,试验组30例,在对照组基础上应用胎盘多肽,观察两组患者治疗前后T细胞亚群及免疫球蛋白情况。结果试验组出T细胞亚群及免疫球蛋白情况均优于对照组,有统计学差异(P <0.05)。结论胎盘多肽应用于肺癌术后患者可以提高患者T细胞亚群及免疫球蛋白,临床疗效优异,值得临床推广。Objective To investigate the clinical efficacy of placenta polypeptide in postoperative patients with lung cancer.Methods From May 2016 to May 2017 in 60 patients receiving joint chemotherapy after surgery for lung cancer in Dalian city by the friendship hospital,were randomized into control group of 30 cases treated with gemcitabine plus cisplatin chemotherapy,30 cases of experimental group,the control group on the basis of the application of placenta polypeptide,observed T cell subsets and immunoglobulin protein before and after treatment in two groups.Results The T lymphocyte subsets and immunoglobulin levels in the experimental group were better than those in the control group,with statistical difference(P<0.05).Conclusion Placenta polypeptide can be used to improve the T lymphocyte subsets and immunoglobulin in patients after lung cancer surgery,and the clinical effect is excellent.It is worthy of clinical promotion.

关 键 词：肺癌术后 吉西他滨 T细胞亚群 免疫球蛋白 

分 类 号：R734.2[医药卫生—肿瘤]