吡嗪缩氨基硫脲Ni(Ⅱ)/Co(Ⅲ)配合物的合成、结构和DNA结合性质（英文）  

Syntheses, Crystal Structures and DNA-Binding Properties of Ni(Ⅱ)/Co(Ⅲ)Complexes with Pyrazine Thiosemicarbazone Ligand

作　　者：吴浩 王元 宋雨飞 张玲 吴伟娜 WU Hao;WANG Yuan;SONG Yu-Fei;ZHANG Ling;WU Wei-Na(College of Chemistry and Chemical Engineering,Henan Key Laboratory of Coal Green Conversion, Henan Polytechnic University,Jiaozuo,Henan 454000,China)

机构地区：[1]河南理工大学化学化工学院,河南省煤炭绿色转化重点实验室,焦作454000

出　　处：《无机化学学报》2018年第11期2057-2062,共6页Chinese Journal of Inorganic Chemistry

基　　金：国家自然科学基金(No.21001040);河南省自然科学基金(No.182300410183,162300410011);河南省教育厅高等校重点(No.19A150001);河南理工大学校内基金(No.T2018-3,J2015-4)资助项目。

摘　　要：合成并通过单晶衍射、元素分析及红外光谱表征了配合物[Ni(L)(OAc)](1)和[Co(L)_2]Cl·4CH_3OH(2)的结构(HL为2-乙酰-3-甲基吡嗪-N-(4-氟苯基)缩氨基硫脲)。单晶衍射结果表明,配合物1中,Ni(Ⅱ)离子中心与缩氨基硫脲配体中的NNS供体和1个单齿醋酸根配位,形成扭曲的平面四边形配位构型;在配合物2中,Co(Ⅲ)离子中心与2个三齿缩氨基硫脲配体配位,拥有扭曲的八面体配位构型。此外,荧光光谱表明配合物1和2与DNA的相互作用强于配体。Two complexes[Ni(L)(OAc)](1)and[Co(L)2]Cl·4CH3OH(2)(HL=2-aceto-3-methylpyrazine N-(4-fluorophenyl)thiosemicarbazone)have been synthesized and structurally determined by single-crystal X-ray diffraction,elemental analysis and IR spectroscopy.X-ray diffraction analysis results show that the Ni(Ⅱ)ion in complex 1 with a distorted square planar geometry is surrounded by one anionic TSC ligand with NNS donor set and one monodentate acetate.By contrast,Co(Ⅲ)ion coordinates with two tridentate TSC ligands,and thus possessing a distorted octahedron coordination geometry.Moreover,the fluorescence spectra indicate that the interactions of complexes 1 and 2 with DNA are stronger than that of the ligand HL.CCDC:1848437,1;1848438,2.

关 键 词：Co(Ⅲ)配合物 DNA结合 Ni(Ⅱ)配合物 吡嗪 缩氨基硫脲 

分 类 号：O614.812[理学—无机化学] O614.813[理学—化学]