硬性透气性角膜接触镜与软性角膜接触镜对中低度近视患者角膜形态的影响  

The effects of soft contact lens and rigid gas permeable contact lens on corneal morphologic changes in mild and low degree myopia

作　　者：周路坦[1] 石迎辉[2] ZHOU Lu-Tan;SHI Ying-Hui(Department of Zhengzhou Railway Vocation&Technical College(,Zhengzhou 450000,Henan Province,China;Department of Ophthalmology,Henan Provincial People’s Hospital,Zhengzhou 450000,Henan Province)

机构地区：[1]郑州铁路职业技术学院医学技术系,河南省郑州市450000 [2]河南省人民医院眼科,河南省郑州市450000

出　　处：《眼科新进展》2018年第11期1059-1061,共3页Recent Advances in Ophthalmology

基　　金：河南省医学科技攻关计划项目(编号:201404054)

摘　　要：目的探讨屈光不正患者长期配戴软性角膜接触镜(soft contact lens,SCL)和硬性透气性角膜接触镜(rigid gas permeable contact lense,RGPCL)对角膜形态参数的影响。方法收集视光学中心验配角膜接触镜的屈光不正患者60例(120眼),按照患者配戴SCL或RGPCL分为SCL组和RGPCL组(两组均为30例60眼),在戴镜前及戴镜后1 a、2a测量2组患者中央角膜厚度、内皮细胞密度、六角形细胞比例及变异系数,并对2组数据进行对比。结果SCL组:戴镜后2 a,中央角膜厚度(509±31)μm较戴镜前(549±26)μm明显下降(P<0.05);角膜内皮细胞密度为(2819.3±169.2)个·mm^(-2),较戴镜前密度(3182. 6±162. 3)个·mm^(-2)减少;六角形细胞比例(51.52±4. 69)%较戴镜前(61.45±4. 58)%降低(P<0.05);内皮细胞变异系数(39. 14±3. 15)较戴镜前(33.47±2.83)增加(P<0.05)。RGPCL组戴镜前后中央角膜厚度、角膜内皮细胞密度、六角形细胞比例及内皮细胞变异系数比较,差异均无统计学意义(均为P>0. 05)。结论与配戴SCL相比,配戴RGPCL对屈光不正患者的角膜形态和功能影响不明显,更适合长期配戴。Objective To evaluate and compare the influence on corneal morphologic parameters about long-term wearing soft contact lens(SCL)and rigid gas permeable contact lens(RGPCL)in patients with ametropia.Methods Totally 60 contact lens users(120 eyes)were divided into two groups:SCL group and RGPCL group,with 30 patients(60 eyes)in each group.Variables including radius of curvature,density of endothelial cells,hexagonal ratio and coefficient of variation were measured and compared before wearing contact lens(CL),one year and two years after wearing CL.Results Two years after SCL wearing,the cornea thickness[(509±31)μm]was significantly lower than that of before wearing[(549±26)μm]in the SCL group(P<0.05);the endothelial cell density[(2819.3±169.2)cells·mm-2]was less than that of before wearing[(3182.6±162.3)cells·mm-2],and endothelial cells hexagonal ratio[(51.52±4.69)%]was lower than that of before wearing[(61.45±4.58)%](all P<0.05),but the variation of endothelial cells(39.14±3.15)was higher than that of before wearing(33.47±2.83)(P<0.05).whereas in the RGPCL group,the cornea thickness,endothelial cell density,endothelial cells hexagonal ratio and coefficient of variation had no significant change two years after wearing RGP.(all P>0.05).Conclusion The influence on corneal morphology and function of ametropia patients wearing RGPCL is not obvious,and RGPCL is more suitable for patients with long-term wearing CL when compared with wearing SCL.

关 键 词：角膜接触镜 角膜曲率 角膜内皮细胞 

分 类 号：R778.1[医药卫生—眼科]