低聚壳聚糖喷雾联合碘伏对预防导管相关性尿路感染的效果研究  

Research on the Effect of Oligochitosan Spray Combined with Iodophor for Preventing Catheter-associated Urinary Tract Infections

作　　者：顾琳琳[1] 冀宝军[2] 洪华[1] GU Linlin;JI Baojun;HONG Hua(School of Nursing,Weifang Medical College,Weifang 261053,China)

机构地区：[1]潍坊医学院护理学院,山东潍坊261053 [2]山东省潍坊市人民医院

出　　处：《中国医学创新》2018年第29期137-140,共4页Medical Innovation of China

基　　金：山东省潍坊市科学技术发展计划项目(2014ws044)

摘　　要：目的:观察低聚壳聚糖喷雾与碘伏联合应用对预防留置尿管相关性尿路感染的效果。方法:选取2014年1-11月潍坊市某三甲医院神经内科收治的脑血管意外且需要留置导尿管的患者共60例,按照患者入院顺序分为试验组和对照组,每组30例。对照组使用0.5%碘伏消毒液棉球进行尿道外口及其周围皮肤常规消毒,试验组将低聚壳聚糖喷雾与0.5%碘伏联合应用在上述部位的护理中。比较两组留置导尿管第3、7、14天中段尿的尿常规、细菌培养阳性率及尿道外口样本细菌定植量。结果:两组患者留置导尿管第3、7天中段尿的尿常规阳性率、细菌培养阳性率比较,差异均无统计学意义(P>0.05);两组患者留置导尿管第14天中段尿的尿常规阳性率、细菌培养阳性率比较,差异均有统计学意义(P<0.05)。两组留置导尿管第3、7天尿道外口细菌定植量比较,差异均无统计学意义(P>0.05);两组留置导尿管第14天尿道外口细菌定植量比较,差异有统计学意义(P<0.05)。结论:采用低聚壳聚糖喷雾与碘伏联合进行会阴护理的方法,能降低需长期(不少于14 d)留置导尿管患者中段尿的尿常规、细菌培养阳性率及尿道外口细菌定植量,从而降低导尿管相关尿路感染的发生率。Objective:To study the effect of oligochitosan spray combined with iodophor for preventing catheter-associated urinary tract infections.Method:A total of 60 patients with cerebrovascular accidents and requiring indwelling urethral catheter were selected from the department of neurology of a first-class hospital in Weifang from January to November 2014,the patients were divided into the experimental group and the control group according to the admission sequence,30 cases in each group.The control group was routinely disinfected with external urethral orifice and its surrounding skin using 0.5%iodophor disinfectant cotton balls,the experimental group applied oligochitosan spray combined with 0.5%iodophor in the nursing of the above sites.Indwelling catheter for 3,7,14 days,the positive rate of urinary routine bacterial culture and bacterial colonization of urethral outcrop samples were compared between the two groups.Result:Indwelling catheter for 3,7 days,the positive rates of urinary routine and bacterial culture in middle segment urine of two groups were compared,the differences were not statistically significant(P>0.05);indwelling catheter for 14 days,the positive rates of urinary routine and bacterial culture in middle segment urine of two groups were compared,the differences were statistically significant(P<0.05).Comparison of bacterial colonization of the external urethral orifice between the two groups on day 3 and 7 of indwelling catheter showed no statistically significant difference(P>0.05);comparison of bacterial colonization amount of external urethral orifice between the two groups at the 14th day of indwelling catheter showed statistically significant difference(P<0.05).Conclusion:The method of using oligochitosan spray combined with iodophor for perineal care can reduce the positive rate of urine conventional bacterial culture and the amount of bacteria colonization in the urethral external mouth of patients with long-term(no less than 14 days)indwelling urethral catheter,thus reducing the incidence

关 键 词：壳聚糖 碘伏 导管相关性尿路感染 

分 类 号：R472[医药卫生—护理学]