胃肠道微生态与幽门螺杆菌相关疾病的研究进展  

Advances in gastrointestinal microbiome and Helicobacter pylori-related diseases

作　　者：王欢 何丛[1] 吕农华[1] WANG Huan;HE Cong;LYU Nong-hua(Dept.of Gastroenterology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第一附属医院消化内科,江西南昌330006

出　　处：《基础医学与临床》2018年第11期1611-1614,共4页Basic and Clinical Medicine

基　　金：国家自然科学基金(81270479;81470832;81670507);国家"十二五"科技重大项目(2011ZX09302-007-03)

摘　　要：人体的胃肠道菌群构成一个庞大的微生态系统,其变化受遗传、饮食、药物和环境等多种因素影响。其中幽门螺杆菌(Hp)是慢性胃炎、消化性溃疡和胃癌等疾病的重要致病因子。明确Hp与胃肠道其他菌群的相互作用,以及该作用对Hp相关疾病发生发展的影响将为Hp致病机制提供新思路。The gastrointerstinal micobiota is a large and complex microecosystem,which is influenced by heredity,diet,drug and environmental factors.Helicobacter pylori(Hp)is an important pathogenic factor of chronic gastritis,peptic ulcer and gastric cancer and other diseases.It can provide a hypothesis about Hp pathogenesis to illustrate the interaction between Hp and other flora in gastrointestinal tract and its effect on the development of Hp-related diseases.

关 键 词：胃肠道 微生态 幽门螺杆菌 胃癌 

分 类 号：R573[医药卫生—消化系统]