微生态制剂联合美沙拉嗪治疗溃疡性结肠炎的效果  

Effect of Microecologic Preparation Combined With Mesalazine in the Treatment of Ulcerative Colitis

作　　者：刘聪[1] LIU Cong(Digestive Second Treatment Area,Jilin Provincial People's Hospital,Changchun Jilin 130021,China)

机构地区：[1]吉林省人民医院消化二疗区,吉林长春130021

出　　处：《中国卫生标准管理》2018年第21期64-66,共3页China Health Standard Management

摘　　要：目的探讨轻中度溃疡性结肠炎患者应用微生态制剂和美沙拉嗪治疗的临床疗效。方法选择轻中度溃疡性结肠炎患者80例,均为我院消化内科2017年3月—2018年3月收治,随机分组,就单用美沙拉嗪治疗(对照组,n=40)与联用微生态制剂治疗(观察组,n=40)的效果展开对比。结果观察组轻中度溃疡性结肠炎患者的临床总有效率为97.5%;对照组临床总有效率为70.0%,组间对比差异有统计学意义(P <0.05)。两组治疗前,内镜下结肠病变程度评分差异无统计学意义(P> 0.05),治疗后均低于治疗前,且观察组低于对照组,差异有统计学意义(P <0.05)。结论轻中度溃疡性结肠炎应用美沙拉嗪的同时联用微生态制剂治疗,可显著提高总有效率,降低炎性反应,改善结肠病变状况。Objective To investigate the clinical effects of microecologic preparation combined with mesalazine in the treatment of mild and moderate ulcerative colitis.Methods 80 cases of mild and moderate ulcerative colitis were selected and treated in our hospital from March 2017 to March 2018.They were randomly divided into groups.The effect of mesalazine(control group,n=40)and combined microecological agents(observation group,n=40)was compared.Results The total effective rate of mild and moderate ulcerative colitis patients in the observation group was 97.5%,the total effective rate in the control group was 70.0%,and the difference between the groups was statistically different(P<0.05).There was no difference between the two groups before the treatment(P>0.05),and the results were lower than those before the treatment,and the observation group was lower than the control group.The difference was statistically significant(P<0.05).Conclusion The treatment of mild and moderate ulcerative colitis in the application of mesalazine combined with microecologic preparation can significantly improve the total effective rate,reduce the inflammatory response and improve the condition of colonic disease.

关 键 词：轻中度 溃疡 结肠炎 美沙拉嗪 微生态 制剂 

分 类 号：R574[医药卫生—消化系统]