Minireview of the clinical efficacy of platelet-rich plasma, platelet-rich fibrin and blood-clot revascularization for the regeneration of immature permanent teeth  

作　　者：Peter E Murray 

机构地区：[1]Department of Endodontics, College of Dental Medicine, Nova Southeastern University

出　　处：《World Journal of Stomatology》2018年第1期1-5,共5页世界口腔医学杂志

摘　　要：The aim of this mini-review was to investigate and compare the clinical efficacy of platelet-rich plasma(PRP) and platelet-rich fibrin(PRF), vs blood clot revascularization(BCR) for the regeneration of immature permanent teeth. The clinical efficacy of PRP, PRF, and BCR to regenerate 90 immature permanent teeth after one year, were compared for their ability to accomplish apical closure, a periapical lesion healing response, root lengthening, and dentinal wall thickening. The 90 cases were published in three different articles. The mean success rate for apical closure after one year was: PRP(89.2%) PRF(80%), and BCR(75.6%). The mean success rate for root lengthening after one year was: BCR(88.9%), PRP(68.2%), and PRF(65%). The periapical lesion healing response was 100% for BCR and 100% for PRP. Dentinal wall thickening was 100% for BCR, and 100% for PRP. All the PRP, PRF, and BCR treatments appeared to be effective. The published clinical results for PRP, PRF, and BCR indicate that these treatments are effective for the regeneration of immature permanent teeth.The aim of this mini-review was to investigate and compare the clinical efficacy of platelet-rich plasma(PRP) and platelet-rich fibrin(PRF), vs blood clot revascularization(BCR) for the regeneration of immature permanent teeth. The clinical efficacy of PRP, PRF, and BCR to regenerate 90 immature permanent teeth after one year, were compared for their ability to accomplish apical closure, a periapical lesion healing response, root lengthening, and dentinal wall thickening. The 90 cases were published in three different articles. The mean success rate for apical closure after one year was: PRP(89.2%) PRF(80%), and BCR(75.6%). The mean success rate for root lengthening after one year was: BCR(88.9%), PRP(68.2%), and PRF(65%). The periapical lesion healing response was 100% for BCR and 100% for PRP. Dentinal wall thickening was 100% for BCR, and 100% for PRP. All the PRP, PRF, and BCR treatments appeared to be effective. The published clinical results for PRP, PRF, and BCR indicate that these treatments are effective for the regeneration of immature permanent teeth.

关 键 词：SAVING IMMATURE teeth Regenerative ENDODONTICS Dental pulp REVASCULARIZATION APICAL closure 

分 类 号：R[医药卫生]