Varicocele repair in severe oligozoospermia: A case report of post-operative azoospermia  

作　　者：Marco Milone Mario Musella Miguel Emilio Sosa Fernandez Paola Maietta Annarita Sasso Loredana Maria Sosa Fernandez Laura Virginia Sosa Fernandez Francesco Milone 

机构地区：[1]Department of Advanced Biomedical Science, University of Naples "Federico Ⅱ",80131 Naples, Italy [2]Embryos, IVF Center in Battipaglia,84100 Salerno, Italy

出　　处：《World Journal of Clinical Cases》2014年第4期94-96,共3页世界临床病例杂志

摘　　要：Varicocele has been implicated as a cause in 35%-50% of patients with primary infertility and up to 81% of men with secondary infertility. Although a large number of reports have shown improvement in the semen parameters after correction of varicocele, other studies have suggested no benefit. We report the first case of azoospermia after surgery in a young infertile male patient with left-sided varicocele and severe oligozoospermia undergoing laparoscopic varicocelectomy. A pregnancy was only achieved with assisted reproductive technology because semen cryopreservation was performed before surgery. In the light of the above, the deterioration of sperm count after varicocele repair in patients with severe oligozoospermia could be due to irreversible impairment of spermatogenesis of such patients, together with the possible temporary damage of the surgical repair. This possible complication could therefore turn the severe oligozoospermia into an indication to perform cryopreservation before surgery, on both clinical and medico-legal grounds. Further research is needed before drawing definitive conclusions regarding the management of varicocele-related severe oligozoospermia.Varicocele has been implicated as a cause in 35%-50% of patients with primary infertility and up to 81% of men with secondary infertility. Although a large number of reports have shown improvement in the semen parameters after correction of varicocele, other studies have suggested no benefit. We report the first case of azoospermia after surgery in a young infertile male patient with left-sided varicocele and severe oligozoospermia undergoing laparoscopic varicocelectomy. A pregnancy was only achieved with assisted reproductive technology because semen cryopreservation was performed before surgery. In the light of the above, the deterioration of sperm count after varicocele repair in patients with severe oligozoospermia could be due to irreversible impairment of spermatogenesis of such patients, together with the possible temporary damage of the surgical repair. This possible complication could therefore turn the severe oligozoospermia into an indication to perform cryopreservation before surgery, on both clinical and medico-legal grounds. Further research is needed before drawing definitive conclusions regarding the management of varicocele-related severe oligozoospermia.

关 键 词：VARICOCELE Fertility SEMEN CRYOPRESERVATION OLIGOZOOSPERMIA 

分 类 号：R698.2[医药卫生—泌尿科学]