supported by the National Natural Science Foundation of China(Grant No.81671511 to PP,No.81871199,No.81501310 to YM).
The extent of spermatogenic impairment on intracytoplasmic sperm injection(ICSI)outcomes and the risk of major birth defects have been little assessed.In this study,we evaluated the relationship between various sperma...
BACKGROUND Epigenetic disruptions have been implicated in some cases of infertility and can serve as therapeutic targets.However,the involvement of epigenetics in infertility has not received adequate attention.AIM Th...
A large proportion of patients with idiopathic spermatogenic failure(SPGF;oligozoospermia or nonobstructive azoospermia[NOA])do not receive a diagnosis despite an extensive diagnostic workup.Recent evidence has shown ...
We should like to thank our patients for agreeing to donate their personal data and allowing the data to be published.We are grateful to Dr.Jiong Gao(BGI Genomics,BGI-Shenzhen,Shenzhen,China)for improving the article.The study was funded by the National Key Research and Development Program of China(Grant No.2018YFC1004903,and 2016YFC1000703);Key Research and Development Program of Zhejiang Province(Grant No.2019C03025);the National Nature Science Foundation of China(Grant No.81801441);and Zhejiang Provincial Natural Science Foundation of China(Grant No.LQ19H090019).
Chromosomal abnormalities and Y chromosome microdeletions are considered to be the two more common genetic causes of spermatogenic failure.However,the relati on ship between chromosomal aberrations and Y chromosome mi...
Follicle-stimulating hormone(FSH)represents a therapeutic option in normogonadotropic patients with idiopathic oligozoospermia.The aim of this review was to evaluate the possible dose-and drug-dependent efficacy of FS...
Supported by the National Natural Science Foundation of China(No.81273767 and 81473690)
Objective: To assess the effect of electroacupuncture(EA) on expression of cytoskeletal proteins from Sertoli cells(SCs) and spermatogenesis in rats with oligozoospermia of insufficiency of Shen(Kidney)essence syndrom...
In the present study, we evaluated the impact of sperm origins and concentration on the clinical outcomes of intracytoplasmic sperm injection (ICSI) cycles. A total of 1201 IC51 cycles were retrospectively analyzed ...
Dear Editor, Intrauterine insemination (IUI) is mainly indicated in cases of unexplained or mild male subfertility. In these cases, gonadotropin ovarian stimulation combined with gonadotropin-releasing hormone (G...
supported by the National Natural Science Foundation of China(No.81300541);the Technology Project of Guizhou Province(No.QKHJZ[2013]2051);the Doctoral Fund of the Affiliated Hospital of Guiyang Medical College(No.C-2012-6),China
Tamoxifen citrate, as the first line of treatment for infertile men with idiopathic oligozoospermia, was proposed by the World Health Organization (WHO), and testosterone undecanoate has shown benefits in semen valu...
Dear Editor, We read the paper by Hammoud et al. in the issue of Asian Journal of Andrology with great interests. This paper revealed that sperm concentration, sperm progressive motility, sperm morphology, and total...