TERATOZOOSPERMIA

作品数:23被引量:108H指数:6
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相关领域:医药卫生更多>>
相关机构:西北妇女儿童医院更多>>
相关期刊:《Journal of Biosciences and Medicines》《Chinese Journal of Integrative Medicine》《Phenomics》《World Journal of Medical Genetics》更多>>
相关基金:国家自然科学基金中国博士后科学基金更多>>
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The relationship between DNA fragmentation and the intensity of morphologically abnormal human spermatozoa
《Asian pacific Journal of Reproduction》2024年第1期22-27,共6页Mercedes González-Martínez Pascual Sánchez-Martín Carmen López-Fernández Stephen D.Johnston Jaime Gosálvez 
Objective:To determine the relationship between teratozoospermia and sperm DNA fragmentation(SDF)in the human ejaculate.Methods:This retrospective study included 100 normozoospermic men as a control cohort(abnormal fo...
关键词:TERATOZOOSPERMIA Sperm morphology Sperm DNA fragmentation Male factor Human reproduction Human fertility 
The identification of AMZ2 as a candidate causative gene in a severe teratozoospermia patient characterized by vacuolated spermatozoa被引量:1
《Asian Journal of Andrology》2024年第1期107-111,共5页Liu Liu Jing Yang Wen-Jing Zhang Yi-Ling Zhou Gui-Jun Zhao Ya Huang Shu-Yan Tang 
This study was supported by the National Natural Science Foundation of China(No.32200485);the University Synergy Innovation Program of Anhui Province(GXXT-2021-071);Shanghai Municipal Science and Technology Major Project(No.2017SHZDZX01).
Teratozoospermia with cephalic defects is one of the most severe types of sperm defects known to date.While several monogenic factors are linked to cephalic abnormalities,such as globozoospermia and macrozoospermia,th...
关键词:AMZ2 male infertility sperm quality TERATOZOOSPERMIA 
Cold and Fertile: Cryopreservation as an Innovative Tool in Addressing Challenges in Teratozoospermia
《Journal of Biosciences and Medicines》2024年第2期274-281,共8页Víctor Manuel Soto-Márquez Jorge Mulia-Rodríguez Daniel Osorio-González 
Teratozoospermia is an infertility issue that affects a significant number of couples of reproductive age. One of the potential causes contributing to the global decline in seminal quality includes factors such as die...
关键词:CRYOPRESERVATION TERATOZOOSPERMIA INFERTILITY 
The role of homozygous LOF variant of the PNLDC1 gene in oligo-astheno-teratozoospermia(OAT)and male infertility
《Asian Journal of Andrology》2023年第6期754-755,共2页Zi-Xin Cheng Li Du Zuping He 
This work was funded by the grant from the National Natural Science Foundation of China(No.32170862).
Dear Editor,An interesting article from Zhao et al.recently published in Asian Journal of Andrology,has shown the association of a novel loss-of function(LOF)variant in PARN-like ribonuclease domain-containing exonucl...
关键词:INFERTILITY LOF terat 
A novel loss-of-function variant in PNLDC1 inducing oligo-astheno-teratozoospermia and male infertility
《Asian Journal of Andrology》2023年第5期643-645,共3页Si-Yi Zhao Lan-Lan Meng Zhao-Li Du Yue-Qiu Tan Wen-Bin He Xiong Wang 
supported by grants from the National Key Research and Development Program of China(2022YFC2702604);the National Natural Science Foundation of China(82171608,82201773,and 81971447);the China Postdoctoral Science Foundation(2022M711119);the Scientific Research Foundation of the Health Committee of Hunan Province(B202301039323 and B202301039518).
Male infertility is a major reproductive disorder,which is clinically characterized by highly heterogeneous phenotypes of abnormal sperm count or quality.To date,five male patients with biallelic loss-of-function(LOF)...
关键词:loss-of-function variant male infertility oligo-astheno-teratozoospermia PARN-like ribonuclease domain-containing exonuclease 1 
Biallelic mutations in WDR12 are associated with male infertility with tapered-head sperm被引量:2
《Asian Journal of Andrology》2023年第3期398-403,共6页Juan Hua Lan Guo Yao Yao Wen Hu Yang-Yang Wan Bo Xu 
This research was supported by the National Key Research and Development Project(No.2019YFA0802600);the National Natural Science Foundation of China(No.82101685,No.82171599,and No.81971333);2020 Basic and Clinical Cooperative Research Promotion Program of Anhui Medical University(No.2020xkjT014).
Teratozoospermia is a rare disease associated with male infertility.Several recurrent genetic mutations have been reported to be associated with abnormal sperm morphology,but the genetic basis of tapered-head sperm is...
关键词:male infertility tapered-head sperm TERATOZOOSPERMIA WD repeat domain 12(WDR12) 
Association between semen collection time and semen parameters:an observational study
《Asian Journal of Andrology》2023年第3期339-344,共6页Shun Bai Xian-Chao Dou Hao-Lin Qi Yan-Song Zhu Yin-Tao Zhang Yi-Xun Liu Xue-Chun Hu Cheng Cao Xian-Hong Tong Bo Xu Li-Min Wu Xiao-Hua Jiang 
This study was supported by the National Natural Science Foundation of China(81901543,81971446,81971333 and 82071709);the National Key R&D Program of China(2018YFC1003900);the National Key Research and Development Project(2019YFA0802600).
The process of semen collection plays a key role in the quality of semen specimens.However,the association between semen collection time and semen quality is still unclear.In this study,ejaculates by masturbation from...
关键词:ASTHENOZOOSPERMIA semen collection time semen quality TERATOZOOSPERMIA 
Mutations in CCIN cause teratozoospermia and male infertility被引量:6
《Science Bulletin》2022年第20期2112-2123,M0004,共13页Yong Fan Chenhui Huang Juan Chen Yanyan Chen Yan Wang Zhiguang Yan Weina Yu Haibo Wu Ying Yang Leitong Nie Sijia Huang Fangfang Wang Haoyu Wang Yunfeng Hua Qifeng Lyu Yanping Kuang Ming Lei 
supported by the National Natural Science Foundation of China(31930063,81771533,81901531,31971137,and 81871163);the National Key Research and Development Program of China(2018YFC2000102,2018YFA0107004,and 2018YFC1003000);the Shanghai Municipal Health Commission and Collaborative Innovation Cluster Project(2019CXJQ01);SHIPM-pi Fund(JY201801);SHIPM-mu Fund(JC201802)。
Teratozoospermia is usually associated with defective spermiogenesis and is a disorder with considerable genetic heterogeneity. Although previous studies have identified several teratozoospermia-associated genes, the ...
关键词:CCIN TERATOZOOSPERMIA Male infertility The calyx Whole-exome sequencing Mouse model 
A Preliminary Study on the Evaluation of Human Sperm Head Morphology with a Domestic Digital Holographic Image System
《Phenomics》2022年第2期130-135,共6页Hong Zhu Yong Zhu Can Sun Feng Jiang 
supported by Shanghai Municipal Science and Technology Major Project(No.:2017SHZDZX01).
The head of sperm was imaged with domestic digital holographic microscopy(DHM),and then the quantitative three-dimensional size information of normal sperm and teratozoospermic sperm was compared and analyzed.DHM sper...
关键词:Digital holographic microscopy(DHM) TERATOZOOSPERMIA Human sperm head morphology 
Epigenetics in the etiology and management of infertility
《World Journal of Medical Genetics》2022年第2期7-21,共15页Tajudeen Olanrewaju Yahaya Danlami M Bashar Esther O Oladele Ja'afar Umar Daniel Anyebe Abdulrazaq Izuafa 
BACKGROUND Epigenetic disruptions have been implicated in some cases of infertility and can serve as therapeutic targets.However,the involvement of epigenetics in infertility has not received adequate attention.AIM Th...
关键词:DNA methylation GAMETOGENESIS INFERTILITY Polycystic ovary syndrome OLIGOZOOSPERMIA TERATOZOOSPERMIA 
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