supported by the Key Research and Development Program of Guangzhou Science and Technology Projects(No.2023B03J1260).
Testicular histology based on testicular biopsy is an important factor for determining appropriate testicular sperm extraction surgery and predicting sperm retrieval outcomes in patients with azoospermia.Therefore,we ...
Azoospermia, defined as a complete absence of spermatozoa in the ejaculate, is a relatively common condition among infertile men. Establishing the etiological diagnosis can be challenging and often requires various in...
supported by the National Natural Science Foundation of China(No.81972909,31971151);the National Key Research and Development Program of China(No.2021YFC2700200);the Bio-ID Center at SJTU,and the K.C.Wong Education Foundation(H.K.).
Germ cell arrest is one kind of important disease in nonobstructive azoospermia(NOA)including spermatogonia arrest,spermatocyte arrest,and round spermatid arrest.1 There is an urgent need to explore the molecular mech...
support from the National Natural Science Foundation of China(No.62275049);the Natural Science Foundation of Fujian Province,China(No.2022J02024);the Fujian Province Joint Fund Project for Scientific and Technological Innovation(2023Y9383).
Male infertility affects 10-15%of couples globally,with azoospermia-complete absence of sperm-accounting for 15%of cases.Traditional diagnostic methods for azoospermia are subjective and variable.This study presents a...
Patients with azoospermia show a prevalence of varicocele of 10.9%and a 14.8%contribution to male infertility.Patients with azoospermia are thought to produce high-quality semen following varicocele treatment.Advising...
supported by the Young and Middle-Aged Key Personnel Training Project of the Fujian Provincial Health Commission(No.2019-ZQN-62);the Fujian Provincial Finance Project(No.BPB-TSX2021).
Although microsurgical vasoepididymostomy(MVE)is an effective treatment for epididymal obstructive azoospermia,some patients may experience delayed patency or suboptimal semen parameters after patency.However,research...
Under normal circumstances, spermatozoa are protected from the immune system by the blood-testis barrier. The breakdown of this barrier is the origin of the synthesis of antisperm antibodies (ASA). The presence of spe...
Background:Some cases of non-obstructive azoospermia(NOA)are characterized by normal clinical parameters,including testicular volume and levels of reproductive hormones,mimicking obstructive azoospermia(OA).Methods:We...
Glutathione peroxidase (GPx) is an antioxidant that plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of enzymatic activity of glutathione peroxidase in the...
This work was supported by the National Natural Science Foundation of China(No.82071931 and No.82130057);the Program for Shanghai Outstanding Medical Academic Leaders(2019LJ18);the Interdisciplinary Program of Shanghai Jiao Tong University(ZH2018ZDA17);the Program from Science and Technology Commission of Shanghai Municipality(20Y11912400);the Clinical Research Innovation Team of Shanghai General Hospital(No.CTCCR-2019B05).
This study aimed to evaluate the ability of rete testis thickness(RTT)and testicular shear wave elastography(SWE)to differentiate obstructive azoospermia(OA)from nonobstructive azoospermia(NOA).We assessed 290 testes ...