Evaluation of Glutathione Peroxidase Enzymatic Activity in Seminal Plasma of Patients Treated at the Institute Pasteur in Cote d’Ivoire  

作　　者：Marie Florence N’Guessan Bi Bali Sery Foua Jonas Vanié Bi N’Gbesso Amos Ekissi Youzan Ferdinand Djohan Founzégué Amadou Coulibaly Allico Joseph Djaman Marie Florence N’Guessan;Bi Bali Sery;Foua Jonas Vanié Bi;N’Gbesso Amos Ekissi;Youzan Ferdinand Djohan;Founzégué Amadou Coulibaly;Allico Joseph Djaman(Biochemistry Unit, Physiology of Reproductive Cells, Institute Pasteur in Ivory Coast, Abidjan, Cote d’Ivoire;The Laboratory of The Medical Sciences Training and Research Unit, Felix Houphouet-Boigny University, Abidjan, Cote d’Ivoire;Medical Sciences Training and Research Unit, Department of Basic and Bioclinical Sciences, Abidjan, Felix Houphouet-Boigny Uni-versity, Abidjan, Cote d’Ivoire;Laboratory of Biotechnology Agriculture and Valorization of Biological Resources, Departement Biosciences, University Félix Hou-phouet-Boigny, Abidjan, Cote d’Ivoire;Agriculture, Fishery Resources and Agro-Industry Training and Research Unit, University of San-Pedro, San-Pedro, Cote d’Ivoire;Departement of Clinical and Fundamental Biochemistry, Institute Pasteur in Cote d’Ivoire, Abidjan, Cote d’Ivoire)

机构地区：[1]Biochemistry Unit, Physiology of Reproductive Cells, Institute Pasteur in Ivory Coast, Abidjan, Cote d’Ivoire [2]The Laboratory of The Medical Sciences Training and Research Unit, Felix Houphouet-Boigny University, Abidjan, Cote d’Ivoire [3]Medical Sciences Training and Research Unit, Department of Basic and Bioclinical Sciences, Abidjan, Felix Houphouet-Boigny Uni-versity, Abidjan, Cote d’Ivoire [4]Laboratory of Biotechnology Agriculture and Valorization of Biological Resources, Departement Biosciences, University Félix Hou-phouet-Boigny, Abidjan, Cote d’Ivoire [5]Agriculture, Fishery Resources and Agro-Industry Training and Research Unit, University of San-Pedro, San-Pedro, Cote d’Ivoire [6]Departement of Clinical and Fundamental Biochemistry, Institute Pasteur in Cote d’Ivoire, Abidjan, Cote d’Ivoire

出　　处：《Advances in Reproductive Sciences》2023年第4期116-126,共11页生殖科学（英文）

摘　　要：Glutathione peroxidase (GPx) is an antioxidant that plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of enzymatic activity of glutathione peroxidase in the seminal plasma of normozoosperm and those of pathological sperm. Thus, the activity of glutathione peroxidase was determined in the seminal plasma of 20 normozoosperms, 9 azoosperms and 31 oligoasthenoteratozoosperms. It was 37.58 ± 3.14 U/L in normozoosperms, 39.39 ± 2.27 U/L in oligoasthenoteratozoosperms, and 29.77 ± 2.62 U/L in azoosperms. The mean GPx enzyme activity of normozoosperms did not differ significantly from that of oligoasthenoteratozoosperms and azoosperms. In contrast, comparison of enzyme activity between abnormal sperms gave a significant difference. This study showed that glutathione peroxidase enzymatic activity is not related to sperm quality.Glutathione peroxidase (GPx) is an antioxidant that plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of enzymatic activity of glutathione peroxidase in the seminal plasma of normozoosperm and those of pathological sperm. Thus, the activity of glutathione peroxidase was determined in the seminal plasma of 20 normozoosperms, 9 azoosperms and 31 oligoasthenoteratozoosperms. It was 37.58 ± 3.14 U/L in normozoosperms, 39.39 ± 2.27 U/L in oligoasthenoteratozoosperms, and 29.77 ± 2.62 U/L in azoosperms. The mean GPx enzyme activity of normozoosperms did not differ significantly from that of oligoasthenoteratozoosperms and azoosperms. In contrast, comparison of enzyme activity between abnormal sperms gave a significant difference. This study showed that glutathione peroxidase enzymatic activity is not related to sperm quality.

关 键 词：Glutathione Peroxidase ANTIOXIDANT OLIGOASTHENOTERATOZOOSPERMIA AZOOSPERMIA Normozoospermia 

分 类 号：O62[理学—有机化学]