supported by the National Natural Science Foundation of China(No.82071709,No.32070850,and No.82171601);the National Key Research and Developmental Program of China(2022YFC2702601 and 2022YFA0806303);the Joint Fund for New Medicine of USTC(YD9100002034).
Male infertility is a worldwide health issue,affecting 8%–12%of the global population.Oligoasthenoteratozoospermia(OAT)represents a severe type of male infertility,characterized by reduced sperm count and motility an...
This study was supported by the National Key Research and Development Program of China(2021YFC2701400 and 2023YFC2705600);the National Natural Science Foundation of China(32288101,32100480,32370654,82271639,32322017,and32200485).
Oligoasthenoteratozoospermia is an important factor affecting male fertility and has been found to be associated with genetic factors.However,there are stll a proportion of oligoasthenoteratozoospermia cases that cann...
supported by the National Key Research and Developmental Program of China(2021YFC2700202,2022YFC2702601,2019YFA0802600,2022YFA0806303);National Natural Science Foundation of China(32470915,32000587,32270901,82171601);Global Select Project(DJK-LX-2022010)of the Institute of Health and Medicine,Hefei Comprehensive National Science Center,Joint Fund for New Medicine of USTC(YD9100002034);Scientific Research Foundation for Scholars of the First Affiliated Hospital of USTC(RC2023054)。
Infertility represents a significant health concern,with sperm quantity and quality being crucial determinants of male fertility.Oligoasthenoteratozoospermia(OAT)is characterized by reduced sperm motility,lower sperm ...
Oxidative stress is one of the main mechanisms responsible for male infertility.Various conditions such as varicocele,obesity,advanced age,and lifestyle can lead to an increase in reactive oxygen species,causing an ox...
Glutathione peroxidase (GPx) is an antioxidant that plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of enzymatic activity of glutathione peroxidase in the...
Aims: To determine the impact of varicocele on the result of the spermogram in a group of hypo-fertile or infertile men. Patients and Method: This was a cross-sectional, descriptive study concerning 264 men collected ...
Supported by the Suzhou Science and Technology Development Plan:Based on the Theory of Collaterals Disease and Damp Disease Explore Promoting Dampness and Dredging Collateral Methods through P38mapk Signaling Pathways Regulate Inflammation Factor of ammatory MechanismⅢRe Type Prostatitis Anti-inflsearch(No.Sysd2018174);Zhangjiagang Science and Technology Plan:Based on the Mapk Pathway Research Runjing Decoction to Oxidative Stress Injury Caused by Weak SD Rats and the Protective Effects of Disease Mechanism Research,(No.ZKS1835);Youth Science and Technology Project of Zhangjiagang Health Plan:Based on the Theory of Essence Chamber to Explore Runjing Decoction Treating Idiopathic Less Weak Sperm Disease Clinical Research and the Analysis of Security(No.ZJGQNKJ201927)。
OBJECTIVE:To investigate the efficacy of Runjing(RJ)extract on oligoasthenoteratozoospermia(OAT)induced by ornidazole(ORN)in rats,and to study the underlying mechanism.METHODS:Twenty-four adult male Sprague-Dawley rat...
This study was supported by grants from the National Key Science Program S&T Program(2018YFC1004900 to YQT);the National Natural Science Foundation of China(81971447 to YQT);the Science and Technology Major Project of the Ministry of Science and Technology of Hunan Province(2017SK1030 to YQT);Graduate Research and Innovation Projects of Central South University(2019zzts734 to YL and 2019zzts322 to WLW)。
Oligoasthenoteratozoospermia(OAT)refers to the combination of various sperm abnormalities,including a decreased sperm count,reduced motility,and abnormal sperm morphology.Only a few genetic causes have been shown to b...
To evaluate the level of antisperm antibody (ASA) in infertile men with oligoasthenoteratozoospermia (OAT). Methods Forty-six infertile men with OAT were enrolled into this study. Sperm samples were screened by th...