OLIGOASTHENOTERATOZOOSPERMIA

作品数:12被引量:15H指数:3
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相关领域:医药卫生更多>>
相关期刊:《Journal of Traditional Chinese Medicine》《Zoological Research》《Advances in Reproductive Sciences》《Open Journal of Medical Imaging》更多>>
相关基金:国家自然科学基金更多>>
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A novel missense mutation of CCDC34 causes male infertility with oligoasthenoteratozoospermia in a consanguineous Pakistani family
《Asian Journal of Andrology》2024年第6期605-609,共5页Nisar Ahmad Meng-Lei Yang Aurang Zeb Jian-Teng Zhou Muhammad Zubair Tanveer Abbas Xiao-Hua Jiang Yuan-Wei Zhang Huan Zhang Wasim Shah Qing-Hua Shi 
supported by the National Natural Science Foundation of China(No.82071709,No.32070850,and No.82171601);the National Key Research and Developmental Program of China(2022YFC2702601 and 2022YFA0806303);the Joint Fund for New Medicine of USTC(YD9100002034).
Male infertility is a worldwide health issue,affecting 8%–12%of the global population.Oligoasthenoteratozoospermia(OAT)represents a severe type of male infertility,characterized by reduced sperm count and motility an...
关键词:CCDC34 consanguineous family male infertility missense mutation OLIGOASTHENOTERATOZOOSPERMIA 
Deficiency of MFSD6L, an acrosome membrane protein, causes oligoasthenoteratozoospermia in humans and mice
《Journal of Genetics and Genomics》2024年第10期1007-1019,共13页Dapeng Zhou Huan Wu Lingbo Wang Xuemei Wang Shuyan Tang Yiling Zhou Jiaxiong Wang Bangguo Wu Jianan Tang Xuehai Zhou Shixiong Tian Shuang Liu Mingrong Lv Xiaojin He Li Jin Hujuan Shi Feng Zhang Yunxia Cao Chunyu Liu 
This study was supported by the National Key Research and Development Program of China(2021YFC2701400 and 2023YFC2705600);the National Natural Science Foundation of China(32288101,32100480,32370654,82271639,32322017,and32200485).
Oligoasthenoteratozoospermia is an important factor affecting male fertility and has been found to be associated with genetic factors.However,there are stll a proportion of oligoasthenoteratozoospermia cases that cann...
关键词:Male fertility OLIGOASTHENOTERATOZOOSPERMIA MFSD6L ACROSOME ICSI 
Homozygous CCDC146 mutation causes oligoasthenoteratozoospermia in humans and mice
《Zoological Research》2024年第5期1073-1087,共15页Jing-Wei Ye Tanveer Abbas Jian-Teng Zhou Jing Chen Meng-Lei Yang Xiong-Heng Huang Huan Zhang Hui Ma Ao Ma Bo Xu Ghulam Murtaza Qing-Hua Shi Bao-Lu Shi 
supported by the National Key Research and Developmental Program of China(2021YFC2700202,2022YFC2702601,2019YFA0802600,2022YFA0806303);National Natural Science Foundation of China(32470915,32000587,32270901,82171601);Global Select Project(DJK-LX-2022010)of the Institute of Health and Medicine,Hefei Comprehensive National Science Center,Joint Fund for New Medicine of USTC(YD9100002034);Scientific Research Foundation for Scholars of the First Affiliated Hospital of USTC(RC2023054)。
Infertility represents a significant health concern,with sperm quantity and quality being crucial determinants of male fertility.Oligoasthenoteratozoospermia(OAT)is characterized by reduced sperm motility,lower sperm ...
关键词:OLIGOASTHENOTERATOZOOSPERMIA Human infertility Sperm flagellum CCDC146 Intraflagellar transport IFT20 
Antioxidant treatment for oligoasthenoteratozoospermia and varicocele:a DBPC trial to evaluate the impact of age and body mass index
《Asian Journal of Andrology》2024年第3期239-244,共6页Gian Maria Busetto Bernarde F Rodrigues Ashraf Virmani Andrea Checchia Antonella Ninivaggi Anna Ricapito Giovanni Barbieri Piero Fischetti Ugo G Falagario Pasquale Annese Nicola d’Altilia Vito Mancini Matteo Ferro Felice Crocetto Angelo Porreca Carlo Bettocchi Luigi Cormio Ashok Agarwal Giuseppe Carrieri 
Oxidative stress is one of the main mechanisms responsible for male infertility.Various conditions such as varicocele,obesity,advanced age,and lifestyle can lead to an increase in reactive oxygen species,causing an ox...
关键词:AGING ANTIOXIDANTS body mass index OLIGOASTHENOTERATOZOOSPERMIA VARICOCELE 
Evaluation of Glutathione Peroxidase Enzymatic Activity in Seminal Plasma of Patients Treated at the Institute Pasteur in Cote d’Ivoire
《Advances in Reproductive Sciences》2023年第4期116-126,共11页Marie Florence N’Guessan Bi Bali Sery Foua Jonas Vanié Bi N’Gbesso Amos Ekissi Youzan Ferdinand Djohan Founzégué Amadou Coulibaly Allico Joseph Djaman 
Glutathione peroxidase (GPx) is an antioxidant that plays an important role in the maintenance of male fertility. The aim of this study was to compare the profile of enzymatic activity of glutathione peroxidase in the...
关键词:Glutathione Peroxidase ANTIOXIDANT OLIGOASTHENOTERATOZOOSPERMIA AZOOSPERMIA Normozoospermia 
Varicocele and Spermogram Abnormality: About 264 Cases at the Fertilia Medical Clinic in Bamako
《Open Journal of Medical Imaging》2023年第3期84-91,共8页Mamadou Dembélé Alassane Kouma Ilias Guindo Souleymane Sanogo Zoumana Cheick Berete Ousmane Traoré Mamadou N’diaye Brahima Doumbia Oncoumba Diarra Issa Cissé Aboubacar Sidiki N’diaye Bandiougou Doucouré Youssouf Yalcouyé Adama Diaman Keita Siaka Sidibe 
Aims: To determine the impact of varicocele on the result of the spermogram in a group of hypo-fertile or infertile men. Patients and Method: This was a cross-sectional, descriptive study concerning 264 men collected ...
关键词:ULTRASOUND Male Infertility VARICOCELE OLIGOASTHENOTERATOZOOSPERMIA 
Abnormal fertilization in ICSI and its association with abnormal semen parameters:a retrospective observational study on 1855 cases被引量:3
《Asian Journal of Andrology》2021年第4期376-385,共10页Konstantinos Pantos Konstantinos Sfakianoudis Evangelos Maziotis Anna Rapani Eleni Karantzali Artemis Gounari-Papaioannou Terpsithea Vaxevanoglou Michael Koutsilieris Mara Simopoulou 
Intracytoplasmic sperm injection(ICSI)efficiently addresses male factor infertility.However,the occurrence of abnormal fertilization,mainly characterized by abnormal pronuclei(PN)patterns,merits investigation.To inves...
关键词:assisted reproduction techniques FERTILIZATION intracytoplasmic sperm injection OLIGOASTHENOTERATOZOOSPERMIA pronuclei semen analysis 
Runjing extract promotes spermatogenesis in rats with ornidazole-induced oligoasthenoteratozoospermia through extracellular signal-regulated kinase signalling,and regulating vimentin expression
《Journal of Traditional Chinese Medicine》2021年第4期581-587,共7页YANG Kai LI Shugen ZHANG Tianyu DONG Panpan ZENG Qingqi 
Supported by the Suzhou Science and Technology Development Plan:Based on the Theory of Collaterals Disease and Damp Disease Explore Promoting Dampness and Dredging Collateral Methods through P38mapk Signaling Pathways Regulate Inflammation Factor of ammatory MechanismⅢRe Type Prostatitis Anti-inflsearch(No.Sysd2018174);Zhangjiagang Science and Technology Plan:Based on the Mapk Pathway Research Runjing Decoction to Oxidative Stress Injury Caused by Weak SD Rats and the Protective Effects of Disease Mechanism Research,(No.ZKS1835);Youth Science and Technology Project of Zhangjiagang Health Plan:Based on the Theory of Essence Chamber to Explore Runjing Decoction Treating Idiopathic Less Weak Sperm Disease Clinical Research and the Analysis of Security(No.ZJGQNKJ201927)。
OBJECTIVE:To investigate the efficacy of Runjing(RJ)extract on oligoasthenoteratozoospermia(OAT)induced by ornidazole(ORN)in rats,and to study the underlying mechanism.METHODS:Twenty-four adult male Sprague-Dawley rat...
关键词:SPERMATOGENESIS OLIGOSPERMIA VIMENTIN extracellular signal-regulated MAP kinases Runjing 
A novel homozygous frameshift mutation in MNS1 associated with severe oligoasthenoteratozoospermia in humans被引量:3
《Asian Journal of Andrology》2021年第2期197-204,共8页Yong Li Wei-Li Wang Chao-Feng Tu Lan-Lan Meng Tong-Yao Hu Juan Du Ge Lin Hong-Chuan Nie Yue-Qiu Tan 
This study was supported by grants from the National Key Science Program S&T Program(2018YFC1004900 to YQT);the National Natural Science Foundation of China(81971447 to YQT);the Science and Technology Major Project of the Ministry of Science and Technology of Hunan Province(2017SK1030 to YQT);Graduate Research and Innovation Projects of Central South University(2019zzts734 to YL and 2019zzts322 to WLW)。
Oligoasthenoteratozoospermia(OAT)refers to the combination of various sperm abnormalities,including a decreased sperm count,reduced motility,and abnormal sperm morphology.Only a few genetic causes have been shown to b...
关键词:intracytoplasmic sperm injection male infertility meiosis-specific nuclear structural 1(MNS1) OLIGOASTHENOTERATOZOOSPERMIA whole-exome sequencing 
Evaluation on Antisperm Antibody in Infertile Men with Oligoasthenoteratozoospermia被引量:2
《Journal of Reproduction and Contraception》2014年第1期49-53,共5页Yi-chao XU Jing LI Wei-bao LIANG Wei-jie ZHU 
To evaluate the level of antisperm antibody (ASA) in infertile men with oligoasthenoteratozoospermia (OAT). Methods Forty-six infertile men with OAT were enrolled into this study. Sperm samples were screened by th...
关键词:antisperm antibody (ASA) SPERM oligoasthenoteratozoospermia (OAT) INFERTILITY 
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