Central Government Funds for Guiding Local Science and Technology Development(No.ZY20198022);Graduate Education Innovation Program of Guangxi University of Traditional Chinese Medicine(No.YCXJ2021067)。
Objective:To investigate the intervention of Xuduan Zhongzi Formula on the epididymis structure of model of oligospermia mice.Methods:Ten of the 45 male mice were labeled as the normal group,and the remaining 35 mice ...
supported by the National Natural Science Foundation of China(No.31801042);the Health and Medical Research Fund(No.04152666 and No.07180576);General Research Fund(No.14115418),and Direct Grant(No.2020.052).
Apparently balanced chromosomal structural rearrangements are known to cause male infertility and account for approximately 1%of azoospermia or severe oligospermia.However,the underlying mechanisms of pathogenesis and...
This work was supported by the grants from the National Key R8cD Program of China(No.2018YFC1003000);the National Natural Science Foundation of China(Nos.81871163 and 81801527).
The dynamic and reversible regulation roles of m^(6)A modification and the characterization of m^(6)A readers have provided new insights into spermatogenesis at the post-transcriptional level.YTHDF2,as an m^(6)A reade...
Objective To observe the clinical effect of herb-separated moxibustion on segmental conception vessel combined with low-frequency transcutaneous electrical acupoint stimulation(TEAS)for asthenospermia and oligospermia...
Supported by the Suzhou Science and Technology Development Plan:Based on the Theory of Collaterals Disease and Damp Disease Explore Promoting Dampness and Dredging Collateral Methods through P38mapk Signaling Pathways Regulate Inflammation Factor of ammatory MechanismⅢRe Type Prostatitis Anti-inflsearch(No.Sysd2018174);Zhangjiagang Science and Technology Plan:Based on the Mapk Pathway Research Runjing Decoction to Oxidative Stress Injury Caused by Weak SD Rats and the Protective Effects of Disease Mechanism Research,(No.ZKS1835);Youth Science and Technology Project of Zhangjiagang Health Plan:Based on the Theory of Essence Chamber to Explore Runjing Decoction Treating Idiopathic Less Weak Sperm Disease Clinical Research and the Analysis of Security(No.ZJGQNKJ201927)。
OBJECTIVE:To investigate the efficacy of Runjing(RJ)extract on oligoasthenoteratozoospermia(OAT)induced by ornidazole(ORN)in rats,and to study the underlying mechanism.METHODS:Twenty-four adult male Sprague-Dawley rat...
Introduction: Male infertility is a public health burden and a psychological dilemma in the life of the affected man. Subjects and Methods: A total of 911 men were studied retrospectively, from 2010 to 2015. Among the...
The reported effects of the glutathione S-transferase (GSTs) genes (GSTM1, GSTTI, and GSTP1) on male factor infertility have been inconsistent and even contradictory. Here, we conducted a case-control study to inv...
Varicocele is prevalent in infertile individuals as well as in normal adolescents and adults.It has an increasing trend with growing age.Infertile individuals with varicocele,develop varying degrees of sperm abnormali...
Fankl is exclusively expressed in the testis from the meiosis phase to the haploid phase of spermatogenesis. In this study, we examined the function of Fankl by establishing a Fankl-knockdown transgenic mouse model. T...