Interventional endoscopic ultrasonography for pancreatic cancer  

作　　者：Kazuo Hara Kenji Yamao Nobumasa Mizuno Susumu Hijioka Akira Sawaki Masahiro Tajika Hiroki Kawai Shinya Kondo Yasuhiro Shimizu Yasumasa Niwa 

机构地区：[1]Department of Gastroenterology,Aichi Cancer Center Hospital,Nagoya 464-8681,Japan [2]Department of Gastrointestinal Surgery,Aichi Cancer Center Hospital,Nagoya 464-8681,Japan

出　　处：《World Journal of Clinical Oncology》2011年第2期108-114,共7页世界临床肿瘤学杂志（英文版）

摘　　要：Endoscopic ultrasonography(EUS)represents the combination of endoscopy and intraluminal ultrasonography.This allows use of a high-frequency transducer(5-20 MHz)that,due to the short distance to the target lesion,provides ultrasonographic images of higher resolution than those obtained from other imaging modalities,including multiple-detector-row-computed tomography,magnetic resonance imaging,and positron emission tomography.EUS is now a widely accepted modality for diagnosing pancreatic diseases.However,the most important limitation of EUS has been the lack of specificity in differentiating between benign and malignant changes.In 1992,EUS-guided fine needle aspiration(FNA)of lesions in the pancreas head was introduced into clinical practice,using a curved linear-array echoendoscope.Since then,EUS has evolved from EUS imaging to EUSFNA and wider applications.Interventional EUS for pancreatic cancer includes EUS-FNA,EUS-guided fine needle injection,EUS-guided biliary drainage and anastomosis,EUS-guided celiac neurolysis,radiofrequency ablation,brachytherapy,and delivery of a growing number of anti-tumor agents.This review focuses on interventional EUS,including EUS-FNA and therapeutic EUS for pancreatic cancer.

关 键 词：ENDOSCOPIC ultrasonography-biliary drainage ENDOSCOPIC ultrasonography-choledochoduodenostomy ENDOSCOPIC ultrasonography-fine needle ASPIRATION ENDOSCOPIC ultrasonography-guided biliary drainage INTERVENTIONAL ENDOSCOPIC ULTRASONOGRAPHY 

分 类 号：R[医药卫生]