Primary duodenal NK/T-cell lymphoma with massive bleeding: A case report  

作　　者：Jian-Zhong Li Jin Tao Dan-Yun Ruan Yi-Dong Yang Ya-Shi Zhan Xing Wang Yu Chen Si-Chi Kuang Chun-Kui Shao Bin Wu 

机构地区：[1]Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University [2]Department of Oncology, The Third Affiliated Hospital of Sun Yat-Sen University [3]Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University [4]Department of Pathology, The Third Affiliated Hospital of Sun Yat-Sen University

出　　处：《World Journal of Clinical Oncology》2012年第6期92-97,共6页世界临床肿瘤学杂志（英文版）

基　　金：Supported by The Major Projects Incubator National Natural Science Foundation of China,No.30971357 and No.82000-3171310;Guangdong Science and Technology Program,No.2009B060300001;Program of Sun Yat-Sen University,No.10ykjc25;One Hundred Talents Program of Sun Yat-Sen University

摘　　要：Primary natural killer/T-cell(NK/T-cell) lymphoma of the gastrointestinal tract is a very rare disease with a poor prognosis, and the duodenum is quite extraordinary as a primary lesion site. Here, we describe a unique case of a primary duodenal NK/T-cell lymphoma in a 26-year-old man who presented with abdominal painand weight loss. Abdominal computed tomography scan demonstrated a hypodense tumor in the duodenum. Because of massive upper gastrointestinal tract bleeding during hospitalization, the patient was examined by emergency upper gastrointestinal endoscopy. Under endoscopy, an irregular ulcer with mucosal edema, destruction, necrosis, a hyperplastic nodule and active bleeding was observed on the duodenal posterior wall. Following endoscopic hemostasis, a biopsy was obtained for pathological evaluation. The lesion was subsequently confirmed to be a duodenal NK/T-cell lymphoma. The presenting symptoms of primary duodenal NK-/T-cell lymphoma in this patient were abdominal pain and gastrointestinal bleeding, and endoscopy was important for diagnosis. Despite aggressive treatments, the prognosis was very poor.Primary natural killer/T-cell(NK/T-cell) lymphoma of the gastrointestinal tract is a very rare disease with a poor prognosis, and the duodenum is quite extraordinary as a primary lesion site. Here, we describe a unique case of a primary duodenal NK/T-cell lymphoma in a 26-year-old man who presented with abdominal painand weight loss. Abdominal computed tomography scan demonstrated a hypodense tumor in the duodenum. Because of massive upper gastrointestinal tract bleeding during hospitalization, the patient was examined by emergency upper gastrointestinal endoscopy. Under endoscopy, an irregular ulcer with mucosal edema, destruction, necrosis, a hyperplastic nodule and active bleeding was observed on the duodenal posterior wall. Following endoscopic hemostasis, a biopsy was obtained for pathological evaluation. The lesion was subsequently confirmed to be a duodenal NK/T-cell lymphoma. The presenting symptoms of primary duodenal NK-/T-cell lymphoma in this patient were abdominal pain and gastrointestinal bleeding, and endoscopy was important for diagnosis. Despite aggressive treatments, the prognosis was very poor.

关 键 词：BLEEDING DUODENUM Natural killer/T-cell LYMPHOMA 

分 类 号：R735.31[医药卫生—肿瘤]