从专利文献角度分析减肥中药的用药规律  

Medication Rule of Obesity from the Perspective of Patent Literature

作　　者：王永[1] 王超[1] 王世华[1] 李向军[1] WANG Yong;WANG Chao;WANG Shihua;LI Xiangjun(Shijiazhuang Yiling Pharmaceutical Co., Ltd., Shijiazhuang 050035, China)

机构地区：[1]石家庄以岭药业股份有限公司,河北石家庄050035

出　　处：《中医药学报》2018年第6期83-88,共6页Acta Chinese Medicine and Pharmacology

摘　　要：目的:研究减肥中药专利文献的用药规律,为减肥中药的新药研发提供思路。方法:检索与减肥相关的中药复方专利,分析药味的出现次数,对出现频次高的药味进行分类,统计。结果:与肥胖有关中药专利文献中,出现频次较高的前十味药材依次为山楂、黄芪、白术、白芷、荷叶、泽泻、大黄、甘草、决明子、苍术,按照功效分类主要集中在补虚、清热、解表、消食、泻下功效的药味中。结论:肥胖与脾、胃、肝、肾等脏腑关系最为密切,多选用补虚、清热、解表、消食、泻下功效的药味,符合中医对肥胖疾病的病机认识,体现了治疗肥胖的中药复方组方特点。Objective:To study the medication rule of obesity from the perspective of TCM patent literature,thus to provide ideas for new drug research of weight-loss.Methods:Patents of TCM compound formula related to weight-loss were reviewed to analyze the frequency of herb's application;on which basis,the top frequency herbs were classified for the statistics.Results:In the TCM literature related to obesity,the top ten herbs with higher application frequency were Shanzha(Hawthorn fruit),Huangqi(Milkvetch root),Baizhu(Atractylodes),Baizhi(Angelica),Heye(Lotus leaves),Zexie(Alisma),Dahuang(Rhubarb),Gancao(Licorice),Juemingzi(Cassia seed)and Cangzhu(Rhizoma atractylodis).The herbs were mainly distributed in the tonic drugs,antipyretic drugs,drugs to relieve exterior,digestive drugs,and purgative drugs according to their actions.Conclusion:Obesity is closely related to Spleen,Stomach,Liver,and Kidney;herbs with the action of tonifying,clearing heat,relieving exterior,helping digestion,or promoting purgation were often used;which comforms to the pathogenesis of obesity in TCM,and it embodies the characteristic of TCM compound formulas treating obesity.

关 键 词：专利文献 肥胖 中药 山楂 荷叶 

分 类 号：R28[医药卫生—中药学]