伴有李琦岛征现象的基底节出血使用甘露醇联合尼莫地平内科综合治疗临床疗效观察  

Observation of clinical curative effect of mannitol combined with nimodipine for basal ganglia hemorrhage accompanied by liqi symptoms

作　　者：施彦[1] 郭渊博[1] 刘旭东[1] 赖文娟[1] Shi Yan;Guo Yuanbo;Liu Xudong;Lai Wenjuan(Department of neurology, people' s hospital of xinfeng county (tongji hospital affiliated to tongji medical college of huazhonguniversity of science and technology), Xinfeng, Jiangxi, 341600, China)

机构地区：[1]信丰县人民医院神经内科(华中科技大学同济医学院附属同济医院对口支援),江西信丰341600

出　　处：《当代医学》2018年第35期48-50,共3页Contemporary Medicine

摘　　要：目的探讨甘露醇联合尼莫地平内科综合治疗对伴有李琦岛征现象的急性基底节出血的疗效。方法抽取本院2016年4月至2017年11月收治的68例伴有李琦岛征现象的急性基底节出血患者为研究对象,根据治疗方式分为常规组、对照组和观察组。常规组采用内科保守治疗方式,对照组实施外科手术疗法,观察组给予甘露醇联合尼莫地平的内科综合治疗方案,比较不同治疗方案临床效果。结果观察组治疗总有效率为91.3%,显著优于常规组59.1%和对照组65.2%(P<0.05);观察组治疗后的颅内血肿体积显著低于常规组和对照组,观察组的预后改善显著优于其他两组(P<0.05)。结论给予伴李琦岛征现象的急性基底节出血患者甘露醇联合尼莫地平的内科综合治疗方案,疗效确切,显著减少血肿体积,且可推动预后顺利开展,值得临床推广应用。objective To explore the curative effect of mannitol combined with nimodipine in the treatment of acute basal ganglia hemorrhage with li qi island syndrome.Methods A total of68cases of acute basal ganglia hemorrhage with li qi's symptoms were selected from our hospital from April2016to November2017.According to the treatment methods,the patients were divided into conventional group,control group and observation group.The conventional group was treated with conservative medical treatment,while the control group was treated with surgical treatment.The observation group was treated with a comprehensive medical treatment regimen of mannitol combined with nimodipine,and the clinical effects of different treatment regimens were compared.Results The total effective rate of treatment in the observation group was91.3%,significantly higher than59.1%in the conventional group and65.2%in the control group(P<0.05).The intracranial hematoma volume of the observation group was significantly lower than that of the conventional group and the control group,and the improvement of the prognosis of the observation group was significantly better than that of the other two groups(P<0.05).Conclusion The combined treatment of mannitol with nimodipine for acute basal ganglia hemorrhage with li qi island sign is effective and can significantly reduce the size of hematoma.

关 键 词：李琦岛征现象 基底节出血 甘露醇 尼莫地平 内科综合治疗 

分 类 号：R743[医药卫生—神经病学与精神病学]