开展微创切除术与低剂量放疗联合应用对早期喉癌治疗的价值  

The Value of Minimally Invasive Resection Combined with Low Dose Radiotherapy in the Treatment of Early Laryngeal Cancer

作　　者：何武斌 赵兴泉[1] 徐鑫 HE Wubin;ZHAO Xingquan;XU Xin(Sichuan Mianyang No.404 Hospital,Mianyang,621000)

机构地区：[1]四川绵阳四〇四医院,621000

出　　处：《实用癌症杂志》2018年第12期1973-1975,1979,共4页The Practical Journal of Cancer

摘　　要：目的分析微创手术治疗联合低剂量放疗用于早期喉癌中的效果及对患者生存质量的影响。方法行手术治疗的早期喉癌患者共52例,用随机数字法分为观察组(低温等离子射频消融术联合低剂量放疗)和对照组(常规开喉手术),对比两组手术时间、住院时间、黏膜恢复评分、并发症发生率、复发率、治疗总有效率和治疗前后生活质量评分。结果观察组手术时间、住院时间较对照组短,黏膜恢复情况评分较对照组高;观察组术后并发症发生率(3. 85%)及复发率(3. 85%)较对照组(19. 23%、15. 38%)低;观察组声音质量Ⅰ、Ⅱ级率(96. 15%)较对照组(88. 46%)高;治疗后观察组生活质量评分高于对照组。差异均具有统计学意义(P均<0. 05)。结论微创手术联合低剂量放疗能提高早期喉癌治疗效果,减少并发症和复发,改善患者生存质量,具有重要临床价值。Objective To analyze the effect of minimally invasive resection combined with low dose radiotherapy on early laryngeal cancer and its influence on the quality of life of the patients.Methods A total of 52 patients with early laryngeal cancer who underwent surgical treatment was randomly divided into observation group(low temperature plasma radiofrequency ablation combined with low dose radiotherapy)and control group(conventional open throat surgery).The two groups were compared with operation time,hospitalization time,mucosa recovery score,complication rate,recurrence rate,total treatment efficiency and life quality score before and after treatment.Results In the observation group,operation time and hospitalization time were shorter than the control group,and mucosal recovery score were higher than the control group.The postoperative complication rate(3.85%)and the recurrence rate(3.85%)in the observation group was lower than those in the control group(19.23%and 15.38%).The observation group I and II level sound quality rate(96.15%)were higher than that in the control group(88.46%),the observation group after treatment,quality of life score were higher than that in the control group.The differences were statistically significant(P<0.05).Conclusion Minimally invasive resection combined with low-dose radiotherapy can improve the early laryngeal cancer treatment effect,reduce complications and recurrence,and improve the quality of life of patients.It has important clinical value.

关 键 词：早期喉癌 微创等离子射频消融 低剂量放疗 效果 生存质量 

分 类 号：R739.65[医药卫生—肿瘤]