先天性上睑下垂合并先天性心脏病临床诊治分析  

Analysis of congenital ptosis accompanied by congenital heart disease

作　　者：曾乐凤[1] 汤政德[1] 王凤丹 张绘莉[1] ZENG Le-feng;TANG Zheng-de;WANG Feng-dan;ZHANG Hui-li(Department of Cardiology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China)

机构地区：[1]上海交通大学医学院附属第九人民医院心内科,上海200011

出　　处：《中国临床医学》2018年第6期929-932,共4页Chinese Journal of Clinical Medicine

基　　金：国家自然科学基金(81570037)~~

摘　　要：目的:研究先天性上睑下垂合并先天性心脏病的情况。方法:回顾性调查1 053例先天性上睑下垂患者先天性心脏病的发病率,并比较不同上睑下垂程度、单双侧上睑下垂患者先天性心脏病的发病率。结果:1 053例先天性上睑下垂患者中,有40例患者同时检出先天性心脏病,发病率为3.80%,高于普通人群中先天性心脏病的发病率。根据眼睑下垂程度分组中,轻度上睑下垂组174例,中度组416例,重度组463例,分别检出先天性心脏病2例(1.15%)、11例(2.64%)和27例(5.83%);重度先天性上睑下垂组先天性心脏病尤其是复合先天性心脏病的发病率明显高于轻度及中度组,差异有统计学意义(P<0.05)。单侧先天性上睑下垂组664例,双侧组389例,两组分别检出先天性心脏病11例(1.66%)、29例(7.46%);双侧上睑下垂组简单和复合先天性心脏病的发病率均明显高于单侧组,差异有统计学意义(P<0.01)。结论:先天性上睑下垂患者同时罹患先天性心脏病的可能性增加,其中以重度或双侧上睑下垂患者先天性心脏病的发病率升高更明显;先天性眼睑疾病的患者有必要进行先天性心脏病筛查。Objective:To investigate the incidence of congenital heart disease in patients with congenital ptosis and the relationship between the two diseases.Methods:The incidence and types of congenital heart disease were retrospectively analyzed in1053patients with congenital ptosis.Results:Forty patients were found to have different types of congenital heart diseases among all of these1053patients with congenital ptosis,yielded an incidence of3.80%,which was higher than that in the general population.Of the1053patients with congenital ptosis,174cases,416cases,and463cases were diagnosed as mild,moderate,and severe ptosis respectively.There were2cases(1.15%),11cases(2.64%),and27cases(5.83%)with congenital heart disease in children with mild,moderate and severe ptosis respectively.Patients with severe ptosis had a significantly higher incidence of congenital heart disease than those with mild or moderate ptosis(P<0.05).And664cases and389cases had unilateral and bilateral ptosis respectively.There were11cases(1.66%),29cases(7.46%)with congenital heart disease in patients with unilateral and bilateral ptosis respectively.Children with bilateral ptosis had a significantly higher incidence of congenital heart disease than those with unilateral ptosis(P<0.01).Conclusions:The incidence of congenital heart disease is increased in patients with congenital ptosis.Higher risk of congenital heart disease may exist in patients with severe and bilateral ptosis.Screening for congenital heart disease in children with ptosis is necessary.

关 键 词：眼睑下垂 先天性心脏病 筛查 

分 类 号：R771.1[医药卫生—眼科]