原发性肝淋巴瘤的影像学表现研究  

Study on the Imaging Findings of Primary Hepatic Lymphoma

作　　者：关静 杜飞舟 魏萌 彭艳梅[2] 陈翼[2] Guan Jing;Du Feizhou;Wei Meng;Peng Yanmei;Chen Yi(Department of Radiology,The General Hospital of Western Theater Command of PLA,Chengdu 610083,China;Kunming General Hospital of PLA,Kunming 650032,China)

机构地区：[1]解放军西部战区总医院放射科,成都610083 [2]解放军昆明总医院,昆明650032

出　　处：《成都医学院学报》2018年第6期671-676,共6页Journal of Chengdu Medical College

基　　金：国家自然科学基金(No:31170007);四川省卫生和计划生育委员会科研课题(No:17PJ494)

摘　　要：目的探讨原发性肝淋巴瘤的CT、MRI、PET综合影像学表现。方法收集解放军西部战区总医院和解放军昆明总医院2008年3月至2017年12月经病理证实的21例原发性肝淋巴瘤患者资料,回顾分析其CT、MRI、PET影像学表现,归纳其影像学特点。结果 21例患者中,单发病灶13例,2个病灶6例,≥3个病灶2例;病灶大多位于肝右叶,肝左叶和尾状叶未见病灶生长;病灶多呈圆形,最大者直径约13.7cm,最小者约2.3cm,平均直径约(5.6±1.3)cm。CT平扫示肝内低密度或稍低密度影,边界清楚,内部密度均匀;增强扫描病灶边缘明显强化,病灶内部轻度强化,14例病灶可见"血管漂浮征"。MRI平扫示病灶T1加权呈低信号,T2加权呈高信号,DWI病灶内部呈高信号,增强扫描病灶强化表现与CT强化相似。18 FDG-PET/CT显像检查见全部肝脏病灶均见放射性异常浓聚,SUV最大值19.3,最小值4.4,平均值12.6;延迟1h显像示所有肝脏病灶SUV值均不同程度升高。结论原发性肝淋巴瘤CT、MRI、PET检查表现具有一定的共性特征,其联合运用可提高肝脏淋巴瘤的诊断水平。Objective To investigate the comprehensive imaging findings of CT,MRI and PET in patients with primary hepatic lymphoma(PHL).Methods The data of21PHL patients confirmed pathologically in The General Hospital of Western Theater Command of PLA and Kunming General Hospital of PLA from March of2008to December of2017were collected.Their imaging findings of CT,MRI and PET were analyzed retrospectively to summarize the imaging characteristics.Results Among the21patients,there were13cases with single lesions,6cases with2lesions,and2cases with no less than3lesions.Most of the lesions were located in the right lobe of the liver and there were no lesions in the left lobe and caudate lobe of the liver.The lesions were mostly round in shape with the largest diameter of about13.7cm,the smallest of about2.3cm,and the average diameter of(5.6±1.3)cm.The Results of CT plain scan showed the shadow with low density or slightly low density in the liver with clear boundary and uniform internal density.In the contrast-enhanced scanning,the edge of the lesion was markedly enhanced,the interior of the lesion was slightly enhanced,and the vascular floating signs could be seen in14cases.The Results of MRI plain scan showed that the T1-weighted lesions showed low signals,the T2-weighted lesions showed hyperintense signals,and the internal DWI lesions showed hyperintense signals.The Results of MRI-enhanced scan were similar to those of CT-enhanced scan.The18FDG-PET/CT imaging Results showed abnormal concentration of radioactivity in all the liver lesions with the maximum SUV value of19.3,the minimum of4.4,and an average of12.6.The1-hour delayed imaging Results showed that the SUV values of all the liver lesions increased in varying degrees.Conclusion The CT,MRI and PET imaging findings of PHL have some common features,so the combined use of CT,MRI and PET can improve the diagnosis of hepatic lymphoma.

关 键 词：肝脏 淋巴瘤 计算机断层扫描 核磁共振成像 正电子发射计算机断层显像 

分 类 号：R735.7[医药卫生—肿瘤]