局部晚期不可切除胰腺癌伽玛射线立体定向放疗与调强放疗疗效分析  

Therapeutic Effect of Gamma-ray Stereotactic Radiotherapy and Intensity-modulated Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer

作　　者：孙艺媛 丁广成[1] 陈鑫[1] 王一帆[1] 时昌立 孟三彦 杨蕊 SUN Yi-yuan;DING Guang-cheng;CHEN Xin;WANG Yi-fan;SHI Chang-li;MENG San-yan;YANG Rui(Gamma Knife Department,the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan Province,450052 China)

机构地区：[1]郑州大学第五附属医院伽马刀科,河南郑州450052

出　　处：《世界复合医学》2018年第4期84-86,共3页World Journal of Complex Medicine

摘　　要：目的分析伽玛射线立体定向放疗和调强放疗治疗局部晚期不可切除胰腺癌的疗效。方法选取该院2015年2月—2017年8月伽玛刀科、放疗科局部晚期不可手术切除胰腺癌患者,各20例,分别行SBRT,IMRT。分析患者治疗前后的临床资料。结果伽玛射线立体定向放疗组有效率80%,调强放疗组有效率70%,对比差异无统计学意义(χ~2=0.533,P>0.05);两种治疗方法都能够减轻患者临床症状(痛、黄),但前者症状缓解更快(痛)(P<0.05)。结论两种放射治疗方法都有着常规治疗无法达到的有效性、精确性、安全性、及非介入性,可作为局部晚期不可切除胰腺癌患者的首选治疗方法。Objective To analyze the efficacy of gamma ray stereotactic radiotherapy and intensity-modulated radiotherapy in the treatment of locally advanced unresectable pancreatic cancer. Methods A total of 20 patients with unresectable pancreatic cancer were randomly selected from the Department of Gamma Knife and Radiotherapy in the hospital from February 2015 to August 2017. SBRT and IMRT were performed. Analyze the clinical data of patients before and after treatment. Results The gammaray stereotactic radio-therapy group was 80% effective, and the intensity-modulated radiotherapy group was 70% effective, and the difference was not statistically significant(χ~2=0.533,P>0.05). Both treatments can alleviate clinical symptoms( Pain, yellow), but the former relieved symptoms faster(pain)(P<0.05). Conclusion Both radiotherapy methods have the efficacy, accuracy, safety, and non-invasiveness that conventional treatment cannot achieve, and can be used as the first choice for patients with locally advanced unresectable pancreatic cancer.

关 键 词：胰腺肿瘤 立体定向放射治疗 调强放射治疗 

分 类 号：R735[医药卫生—肿瘤]