帕金森病外周血生物标记物的研究及评价  

Study and evaluation of biomarkers in peripheral blood of Parkinson's disease

作　　者：陈昱升 CHEN Yu-Sheng(Xuzhou Medical University,Xuzhou 221000,China)

机构地区：[1]江苏省徐州医科大学,江苏徐州221000

出　　处：《转化医学电子杂志》2018年第12期105-107,共3页E-Journal of Translational Medicine

摘　　要：帕金森病属于典型神经内科疾病,其本质为运动障碍疾病,在临床上又称震颤麻痹,多见于中老年人,同时存在一系列非运动型障碍,包括运动迟缓和减少、肢体强直以及抖动,同时包括姿势及步态异常。随着临床研究的逐渐深入,针对其外周血生物标记物的研究进展获得极大突破,临床诊疗效果得到有效提升,本文在此背景下,针对帕金森病的病症机理,深入分析外周血生物标记物的相关联系,以期为早期临床诊疗提供更加详细的参考依据。Parkinson's disease is a typical neurological disease,which is characterized by dyskinesia.It is also known as tremor and paralysis in the clinic and is more common in middle-aged and elderly people.There are series of non-motor disorders,including bradykinesia and hypokinesia,limb rigidity and shaking,and abnormal posture and gait.With the deepening of clinical research,great breakthroughs have been made in the research of biomarkers in peripheral blood,and the clinical efficacy has been effectively improved.In view of the pathogenesis of Parkinson s disease,this papers analyzed the correlation of biomarkers in peripheral blood,in order to provide reference for early clinical diagnosis and treatment.

关 键 词：帕金森病 外周血 生物标记物 

分 类 号：R742.5[医药卫生—神经病学与精神病学]