1例良性脊索细胞瘤的临床病理特点及文献复习  

Clinicopathological features of a case of benign notochordal cell tumour and literature review

作　　者：温永琴[1] 何建芳[1] WEN Yong-qin;HE Jian-fang(Department of Pathology,Dongguan People’s Hospital,Dongguan 523000,China)

机构地区：[1]广东省东莞市人民医院病理科,广东东莞523000

出　　处：《广东医科大学学报》2018年第6期653-657,共5页Journal of Guangdong Medical University

基　　金：东莞市社会科技发展项目(No.201650715001384)

摘　　要：目的总结良性脊索细胞瘤(BNCT)的临床病理特点。方法报道1例BNCT的临床、影像学、病理特征。结果患者女性,53岁,颈肩部酸痛、麻木3个月。MRI、CT显示颈4椎体左侧占位性病变。行颈椎肿瘤切除、后路内固定术。病理检查发现肿瘤组织由胞质透亮的脂肪样细胞和胞质淡染细胞构成,以脂肪样细胞为主,无明显异型性。免疫组化显示肿瘤细胞表达CK、vimentin、S-100、EMA、PGP9.5。结论 BNCT是罕见的脊索源性肿瘤,预后良好。Objective To summarize the clinicopathological features of benign notochordal cell tumor(BNCT).Methods Clinical,imageological and pathological characteristics of a case of BNCT were reported.Results A 53-year-old woman presented with a 3-month history of pain and numbness on the neck and shoulders.MRI and CT scan revealed an occupying lesion on the left side of 4 th cervical vertebra.The tumor was resected with posterior cervical fixation.Pathologically,the tumor cells were lack of atypia,and comprised mainly adipocyte-like cells with clear cytoplasm and occasionally cells with eosinophilic cytoplasm.Immunohistochemically,the tumor cells were positive for CK,vimentin,S-100,EMA,and PGP9.5.Conclusion BNCT is a rare notochord-derived tumor with a favorable prognosis.

关 键 词：骨肿瘤 脊索细胞瘤 

分 类 号：R738[医药卫生—肿瘤]