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作 者:李晓东 曹有军 LI Xiaodong;CAO Yuojun(epartment of Integrated Chinese and Western Medicine,BenQ Medical Center BenQ Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Nanjing 210019,China)
机构地区:[1]南京明基医院南京医科大学附属明基医院中西医结合科,江苏南京210019
出 处:《中国医药导报》2019年第1期119-122,共4页China Medical Herald
基 金:国家临床重点专科建设项目(卫办医政函[2011]873号)
摘 要:目的寻找中医防治放射性食管炎的辨证用药规律。方法本文通过搜索中国知网(CNKI)、维普(VIP)、万方(Wanfang)三大中文数据库中1990年1月~2017年10月的文献,筛选出44篇使用中医防治放射性食管炎的文献,对文献中的辨证证型和处方用药频率数据进行提取整理。结果辨证出现最频繁的三种证型分别是"热毒炽盛""耗阴伤津""瘀热互结",文献占比分别为95.4%、56.8%、40.9%。用药类别出现最频繁的分别是"清热解毒药""养阴生津药""凉血活血药",文献占比分别为95.4%、95.4%、40.9%。结论中医治疗放射性食管炎的主要辨证分型是"热毒炽盛,耗阴伤津",放射后期会出现血瘀证型,治疗主要使用清热解毒、养阴生津、活血化瘀这三类药物。Objective To explore the medication rules of TCM differentiation in the prevention and treatment of radiation esophagitis.Methods By searching for articles in three Chinese databases including China National Knowledge Internet(CNKI),VIP and Wanfang database from January 1990 to October 2017,44 articles with TCM in the prevention and treatment of radiation esophagitis were screened out.The data on syndrome differentiation and prescription frequency in the articles was extracted and collated.Results The three most frequent syndromes in syndrome differentiation were“blazing heat-toxin”“yin depletion and consumption of body-fluid”and“blood stasis and heat accumulation”,accounting for 95.4%,56.8%and 40.9%,respectively.The most frequent medications included“heat-clearing and detoxifying drug”,“nourishing yin and promoting the secretion of body-fluid drug”and“cooling blood and activating blood circulation drug”,accounting for 95.4%,95.4%and 40.9%,respectively.Conclusion The main syndrome differentiation of TCM in radiation esophagitis includes“excessive heat and toxin”and“yin depletion and consumption of body-fluid”.In the late stage of radiation,blood stasis syndrome may occurs.Heat-clearing and detoxifying,nourishing yin and promoting the secretion of body-fluid and cooling blood and activating blood circulation drugs are mainly used in the treatment.
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