全球首例人感染H9N2亚型禽流感病毒肺炎的临床影像学描述性研究  

A descriptive study of the global first case of pneumonia caused by human-infected avian influenza virus H9N2

作　　者：侯文忠[1] 张倩倩 罗彩梅[1] 陆普选 HOU Wen-zhong;ZHANG Qian-qian;LUO Cai-mei;LU Pu-xuan(Department of Radiology,Meizhou People's Hospital,Guangdong Meizhou 511021,China;Department of Radiology,the third people's Hospital of Shenzhen Medical University,Guangdong Shenzhen 518112,China)

机构地区：[1]广东省梅州市人民医院放射科,广东梅州514021 [2]广东医科大学附属深圳市第三人民医院放射科,广东深圳518112

出　　处：《新发传染病电子杂志》2016年第1期18-22,共5页Electronic Journal of Emerging Infectious Diseases

基　　金：深圳市知识创新计划重点项目(JCY20130401164750006;JCY20150207181301)

摘　　要：目的探讨人感染H9N2亚型禽流感病毒肺炎的临床影像表现特点。方法以2016年6月18日确诊的一例发生于广东省梅州市的人感染H9N2亚型病毒肺炎患儿病例进行描述性研究。结果患者为儿童,以咳嗽为首发症状,初为白色黏痰后为黄色黏稠痰,有发热波动,影像表现以渗出性斑片状磨玻璃密度影为主,恢复期仍可见肺间质纤维化。经抗病毒及对症治疗后患儿痊愈出院。结论人感染H9N2后,除有类流感症状外,双肺CT还可表现为渗出性病灶。临床医师对于有禽类接触史,并有发热症状、肺部感染的儿童,应考虑病毒感染的可能,尽早诊断和给予抗病毒治疗是改善预后的关键。Objective To discuss the imaging features of pneumonia caused by human-infected avian influenza virus H9N2.Methods A descriptive study was carried out on a case of pneumonia caused by human-infected avian influenza virus H9N2 in Meizhou,Guangdong Province,on June 18,2016.Results The patient was a child with cough,and white phlegm was detected followed by yellow sticky sputum,accompanying with fever.Imaging features included exudative patchy ground glass opacity,and pulmonary fibrosis was visible during the recovery period.The patient was discharged from hospital after antiviral and symptomatic treatments.Conclusion For pneumonia caused by human-infected avian influenza virus H9N2,except for the symptoms of influenza,exudative focus was present in bilateral lung CT images.Clinicians should consider the possibility of viral infection in children who had contact history with poultry and got fever and pulmonary infection.Early diagnosis and antiviral therapy are important to improve the prognosis.

关 键 词：禽流感病毒 H9N2 肺炎 影像学表现 

分 类 号：R725.1[医药卫生—儿科] R816.92[医药卫生—临床医学]