supported by National Natural Science Foundation of China[Grant number:32272992(JP),31772775(JP)];National Key Research and Development Program of China[Grant number:2021YFD1800205(JP)].
The H9N2 subtype avian influenza virus(AIV)continues to propagate and undergo evolution within China,thereby posing a significant threat to the poultry industry.This study encompassed the collection of 436 samples and...
supported by the National Natural Science Foundation of China(32273037 and 32102636);the Guangdong Major Project of Basic and Applied Basic Research(2020B0301030007);Laboratory of Lingnan Modern Agriculture Project(NT2021007);the Guangdong Science and Technology Innovation Leading Talent Program(2019TX05N098);the 111 Center(D20008);the double first-class discipline promotion project(2023B10564003);the Department of Education of Guangdong Province(2019KZDXM004 and 2019KCXTD001).
A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,...
Background:The threat of avian influenza a subtype avian influenza A(H9N2)virus remains a significant concern,necessitating the exploration of novel antiviral agents.This study employs network pharmacology and computa...