阿立哌唑与利培酮治疗晚发精神分裂症疗效对比分析  

Comparative Analysis of the Efficacy of Aripiprazole and Risperidone in the Treatment of Late-onset Schizophrenia

作　　者：陈晓芹 牛娟[2] 刘丽华[1] CHEN Xiaoqin;NIU Juan;LIU Lihua(NO.6 Ward,Qingdao Mental Health Center,Qingdao Shandong 266034,China;Psychological Clinic,The Affiliated Hospital of Qingdao University,Qingdao Shandong 266021,China)

机构地区：[1]青岛市精神卫生中心六病房,山东青岛266034 [2]青岛大学附属医院心理门诊,山东青岛266021

出　　处：《中国继续医学教育》2019年第3期115-117,共3页China Continuing Medical Education

摘　　要：目的对比分析阿立哌唑同利培酮治疗晚发精神分裂症的疗效。方法选取医院2017年1月—2018年1月收治的晚发精神分裂症患者100例作为研究对象。采用随机数字表法,将100例患者随机分为两组,每组各50例。两组患者分别给予阿立哌唑以及阿立哌唑治疗同利培酮联合给药治疗。结果采用阿立哌唑给药的观察组的治疗总有效率为92%,高于采用利培酮给药的对照组72%的总有效率,差异具有统计学意义(P <0.05);观察组患者不良反应发生率为20%,低于对照组44%的不良反应发生率,差异具有统计学意义(P <0.05)。结论阿立哌唑治疗晚发精神分裂症疗效较利培酮更为确切。Objective To study and analyze the efficacy of aripiprazole and risperidone in the treatment of late-onset schizophrenia.Methods 100 patients with late-onset schizophrenia admitted to our hospital from January 2017 to January 2018 were selected as the study subjects.Using random number table method,100 patients were randomly divided into two groups,50 cases in each group.The two groups were treated with aripiprazole and aripiprazole combined with risperidone.Results The total effective rate of the observation group treated with aripiprazole was 92%,which was higher than 72%of the control group treated with risperidone(P<0.05).The incidence of adverse reactions in the observation group was 20%,which was lower than 44%in the control group(P<0.05).Conclusion Aripiprazole is more effective than risperidone in the treatment of late-onset schizophrenia.

关 键 词：阿立哌唑 利培酮 晚发精神分裂症 疗效 

分 类 号：R749[医药卫生—神经病学与精神病学]