甲状腺透明细胞癌11例临床病例分析  

Clinical analysis of 11 cases of thyroid clear cell carcinoma

作　　者：杜心 张清富 DU Xin;ZHANG Qing-fu(Department of Pathology,Liaohua Hospital of Liaoyang,Liaoyang 111003,China)

机构地区：[1]辽宁省辽阳市辽化医院病理科,辽宁辽阳111003

出　　处：《中国医药指南》2019年第1期49-49,共1页Guide of China Medicine

摘　　要：目的观察甲状腺透明细胞癌的临床病理特点及鉴别诊断。方法收集甲状腺透明细胞癌11例,分别进行HE染色和免疫组织化学染色。结果 11例甲状腺透明细胞癌均为甲状腺滤泡癌的亚型。结论甲状腺透明细胞癌罕见,占所有甲状腺肿瘤0.5%～1.7%,该肿瘤以胞质透明的细胞为主(> 75%),胞质的这种特征可能是由于糖原、脂质、黏液、甲状腺球蛋白、其他囊泡或扩张的线粒体蓄积所致。超声、CT检查多为实性包块。确诊需要依靠病理诊断和免疫组织化学染色,治疗采用手术为主的综合措施。Objective To observe the clinicopathological features and differential diagnosis of thyroid clear cell carcinoma.Methods Eleven cases of thyroid clear cell carcinoma were collected and stained with HE and immunohistochemistry.Results Eleven thyroid clear cell carcinomas were subtypes of thyroid follicular carcinoma.Conclusion Clear cell thyroid cell carcinoma is rare,accounting for 0.5%-1.7%of all thyroid tumors.The tumor is mainly cytoplasmic and transparent cells(﹥75%).This characteristic of cytoplasm may be due to glycogen,lipid and mucus,caused by thyroglobulin,other vesicles or expanded mitochondrial accumulation.Ultrasound and CT examinations are mostly solid masses.The diagnosis needs to rely on pathological diagnosis and immunohistochemical staining to treat comprehensive measures based on surgery.

关 键 词：甲状腺 透明细胞癌 病理诊断 

分 类 号：R736.1[医药卫生—肿瘤]