乙肝肝硬化患者胃镜表现相关性因素的分析  

Analysis of the factors associated with the gastroscopic manifestations in patients with HBV-related cirrhosis

作　　者：戴颖[1] 陈川英[1] 程全红[1] DAI Ying;CHEN Chuanying;CHENG Quanhong(The Ninth Hospital of Nanchang,Nanchang 330000,China)

机构地区：[1]江西省南昌市第九医院肝三科,南昌330000

出　　处：《江西医药》2018年第12期1372-1375,共4页Jiangxi Medical Journal

摘　　要：目的通过观察乙肝肝硬化患者胃镜下的表现,进行肝功能分级、门静脉内径、HP感染相关性因素的分析,从而通过干预达到降低上消化道出血的风险。方法对南昌市第九医院166例乙肝肝硬化患者进行回顾性分析,记录其胃镜下食管静脉曲张、门脉高压性胃病(PHG)、溃疡及幽门螺杆菌(HP)感染的情况,探讨肝功能Chid-pugh分级、门静脉内径、HP感染与胃镜下表现的关系。结果本组患者HP阳性率为43.37%(72/166)。HP阳性率与性别、年龄关系不大。随着肝功能损害加重,食管静脉曲张及PHG的发生率逐渐增加(P<0.05)。溃疡发生率与肝功能分级之间无相关性(P>0.05)。食管静脉曲张程度与HP感染无相关性(P>0.05);PHG分型与HP感染经检验,无与轻型PHG、轻与重型PHG相比P>0.05;无与重型PHG相比P<0.05;消化性溃疡发生与HP感染成正相关(P<0.05)。食管静脉曲张程度与门静脉内径关系经检验,无与中、重度曲张组,轻与重度曲张组相比P<0.05;无与轻度曲张组、轻与中度曲张组、中与重度曲张组相比P>0.05;PHG分型与门静脉内径关系,无与重型PHG,轻与重型PHG相比P<0.05;无与轻型PHG相比P>0.05;溃疡发病率与门静脉内径呈正相关(P<0.05)。结论积极治疗肝脏疾病,降低门静脉压力及根治HP可有效降低上消化道出血风险。Objective To analyze the correlation between the gastroscopic manifestations and liver function classification,portal vein diameter,HP infection By observing the gastroscopic manifestations of the HBV-related cirrhosis.To reduce the risk of upper gastrointestinal bleeding by intervention.Methods 166 patients with HBV-related cirrhosis diagnosed in Ninth hospital Analysis of the factors associated with the gastroscopic manifestations in patients with HBV-related cirrhosis.of NanChang were selected.Esophageal varices,portal hypertensive gastropathy(PHG),ulcers and helicobacter pylori(HP)infection were recorded.Results The positive rate of HP in cirrhotic patients was 43.37%(72/166).There were no statistically significant differences in gender and age in HP positive groups.With the aggravation of liver function damage,the incidence of esophageal varicose veins and PHG increased gradually(P<0.05).There was no correlation between the incidence of ulcer and liver function grade(P>0.05).There was no correlation between the degree of esophageal varices and HP infection(P>0.05).There were no statistically significant differences in HP infection between no PHG group and light PHG group,light PHG group and heavy PHG group P>0.05.There were statistically significant differences in HP infection between no PHG group and light PHG group,light PHG group and heavy PHG group P<0.05.The occurrence of peptic ulcer was positively correlated with Hp infection(P<0.05).There showed significant differences in the relationship between the degree of esophageal varicosity and the inner diameter of portal vein in no and moderate varicose groups,no and severe varicose groups,Light and severe varicose groups P<0.05.There was no comparison with no and light varicose groups,light and moderate groups,moderate and severe groups P>0.05;There were statistically significant differences between PHG and inner diameter of portal vein in no PHG group and heavy PHG group,light PHG group and heavy PHG group P>0.05,but the difference was not statistically s

关 键 词：乙肝肝硬化 肝功能分级 门静脉内径 幽门螺杆菌 上消化道出血 

分 类 号：R575.2[医药卫生—消化系统]