绝经后妇女宫颈高危型HPV感染及宫颈病变的临床分析  

Clinical Analysis of Cervical High-risk HPV Infection and Cervical Lesions in Postmenopausal Women

作　　者：李赟[1] LI Yun(Department of Obstetrics and Gynecology, Wujin Hospital of Traditional Chinese Medicine, Changzhou, Jiangsu Province, 213161 China)

机构地区：[1]江苏省常州市武进中医医院妇产科,江苏常州213161

出　　处：《中外医疗》2018年第35期66-68,共3页China & Foreign Medical Treatment

摘　　要：目的探究分析绝经后妇女宫颈高危型HPV感染及宫颈病变的发生特点及相关的处理措施。方法 2016年1月—2017年12月在该院妇科门诊和体检中心查高危型HPV共9 820例。绝经后查1 209例,其中阳性者388例。阳性检出率32.09%(388/1 209);绝经前查8 611例其中阳性者2 036例,阳性检出率23.64%(2 036/8 611),选取上述人群中因高危型HPV感染在该院门诊行阴道镜检查,资料完整的绝经后妇女100例作为研究对象,分为观察组,找出相同亚型高危型HPV感染和相同TCT结果的绝经前妇女100例为对照组,分别对两组患者行阴道镜检查活检。结果观察组发现CIN1及以上病变35例,病变率为35%;对照组发现CIN1及以上病变54例,病变率为54%。观察组的数值结果显著低于对照组患者,组间差异有统计学意义(χ2=3.215,P<0.05)。结论绝经后妇女高危型HPV感染及宫颈病变的发生率较低,应了解绝经后妇女阴道镜检查及宫颈病变等特点以及检查和治疗过程中的特殊性,以便及早发现及早治疗绝经后妇女宫颈癌前病变,减少漏诊率。Objective To investigate the characteristics of cervical high-risk HPV infection and cervical lesions in postmenopausal women and the related treatment measures.Methods From January 2016 to December 2017,a total of 9 820 high-risk HPV patients were investigated at the gynaecological clinic and physical examination center of the hospital.1 209 cases were examined after menopause,of which 388 were positive.The positive detection rate was 32.09%(388/1 209); the pre-menopausal examination was 8 611 cases,among which 2 036 were positive,the positive detection rate was 23.64%(2 036/8 611).The above-mentioned population was selected for high-risk HPV infection in our hospital outpatient vagina mirror examination,100 cases of postmenopausal women with complete data were included in the observation group.100 cases of premenopausal women with the same subtype of high-risk HPV infection and the same TCT results were selected as the control group.Mirror biopsy were implemented in both groups.Results In the observation group,35 cases of CIN1 and above were found,and the lesion rate was 35%.In the control group,54 cases of CIN1 and above were found,and the lesion rate was 54%.The numerical results of the observation group were significantly lower than those of the control group,and the difference between the groups was statistically significant(χ^2=3.215,P<0.05).Conclusion The incidence of high-risk HPV infection and cervical lesions in postmenopausal women is low.It is necessary to understand the characteristics of colposcopy and cervical lesions in postmenopausal women and the special characteristics during examination and treatment,so as to detect early and early treatment of cervical cancer in postmenopausal women with precancerous lesions,so as to reduce the rate of missed diagnosis.

关 键 词：绝经后妇女 宫颈高危型HPV感染 宫颈病变 临床分析 

分 类 号：R737.33[医药卫生—肿瘤]