Ghost cell odontogenic carcinoma of the jaws: Report of two cases and a literature review  

作　　者：Meng-Qi Jia Jun Jia Li Wang Hai-Xiao Zou 

机构地区：[1]State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education,School and Hospital of Stomatology, Wuhan University [2]Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University [3]Department of Pathology, School and Hospital of Stomatology, Wuhan University [4]Department of Stomatology, the Second Affiliated Hospital of Nanchang University

出　　处：《World Journal of Clinical Cases》2019年第3期357-365,共9页世界临床病例杂志

基　　金：Supported by National Natural Science Foundation of China,No.81502745;Science and Technology Project of Jiangxi Province,No.GJJ170014

摘　　要：BACKGROUND Ghost cell odontogenic carcinoma(GCOC) is a rare malignant odontogenic epithelial tumor with features of benign calcifying odontogenic cysts. Herein, we report two new cases of GCOC and systematically review the previous literature.CASE SUMMARY In case 1, a 46-year-old man complained of painless swelling of the right maxilla for 3 years, with a 1-mo history of hemorrhinia in the right nasal cavity. In case 2,a 72-year-old man was referred to our hospital with a chief complaint of painful swelling of the right mandible. Initially, the preliminary diagnoses were ameloblastomas. Thus, the two patients underwent resection of the tumor under general anesthesia. Finally, immunohistochemical examination confirmed the diagnosis of GCOC. The patient in case 1 was followed for 2 years, with no evidence of recurrence. However, the patient in case 2 was lost to follow-up.CONCLUSION GCOC is a rare malignant odontogenic epithelial tumor with high recurrence.Local extensive resection is necessary for the definitive treatment of GCOC.BACKGROUND Ghost cell odontogenic carcinoma(GCOC) is a rare malignant odontogenic epithelial tumor with features of benign calcifying odontogenic cysts. Herein, we report two new cases of GCOC and systematically review the previous literature.CASE SUMMARY In case 1, a 46-year-old man complained of painless swelling of the right maxilla for 3 years, with a 1-mo history of hemorrhinia in the right nasal cavity. In case 2,a 72-year-old man was referred to our hospital with a chief complaint of painful swelling of the right mandible. Initially, the preliminary diagnoses were ameloblastomas. Thus, the two patients underwent resection of the tumor under general anesthesia. Finally, immunohistochemical examination confirmed the diagnosis of GCOC. The patient in case 1 was followed for 2 years, with no evidence of recurrence. However, the patient in case 2 was lost to follow-up.CONCLUSION GCOC is a rare malignant odontogenic epithelial tumor with high recurrence.Local extensive resection is necessary for the definitive treatment of GCOC.

关 键 词：Ghost cell Odontogenic carcinoma Pathological features Treatment 

分 类 号：R[医药卫生]