凝血酶、生长抑素联合奥美拉唑治疗上消化道出血的临床分析  

Clinical Analysis of Thrombin and Somatostatin Combined with Omeprazole in the Treatment of Upper Gastrointestinal Bleeding

作　　者：汤仕龙 TANG Shi-long(The Affiliated Hospital of Jiangxi Normal University,Nanchang,Jiangxi 330027)

机构地区：[1]江西师范大学校医院,江西南昌330027

出　　处：《赣南医学院学报》2018年第12期1212-1213,1216,共3页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：目的:分析凝血酶、生长抑素联合奥美拉唑用于治疗上消化道出血的临床治疗效果。方法:80例急性上消化道出血的患者按入院先后顺序进行分组,分为研究组和对照组各40例。2组患者同样使用奥美拉唑40 mg治疗,研究组患者使用奥美拉唑联合凝血酶及生长抑素三联治疗,比较治疗后两组患者的临床疗效及药物不良反应的发生情况。结果:研究组总的治疗有效率为95%,对照组为80%,2组比较差异有统计学意义(P <0. 05)。研究组药物不良反应率为15%,对照组为32. 5%,2组比较差异有统计学意义(P <0. 05)。结论:凝血酶、生长抑素联合奥美拉唑治疗上消化道出血患者疗效显著,安全性高,不良反应发生率低,值得临床推广应用。Objective:To analyze the clinical treatment effect of thrombin and somatostatin combined omeprazole on upper gastrointestinal hemorrhage.Method:We study 80 cases of acute upper gastrointestinal hemorrhage patients,who are equally divided into the research group and the controlled group with their respective 40 cases according to their admission ordering.Both groups'patients are treated with 40 mg omeprazole while the research group patients are treated jointly with omeprazole combined thrombin and somatostatin.We compare the clinical curative effect and adverse drug reaction after treatment of these two groups'patients.Results:The research group total effectiveness amounts to 95%while the controlled group effectiveness amounts to 80%.These two groups'total effectiveness difference is statistically significant(P<0.05).Adverse drug reaction rate is 15%for the research group and 32.5%for the control group.These two groups'adverse drug reaction rate difference is also statistically significant(P<0.05).Conclusion:Obvious therapeutic effect for upper gastrointestinal hemorrhage patients can be obtained by taking treatment of thrombin somatostatin combined with omeprazole,which is highly safe and incurs low incidence of adverse reactions and worthy clinical popularization and application.

关 键 词：凝血酶 生长抑素 奥美拉唑 上消化道出血 

分 类 号：R573.2[医药卫生—消化系统]