太极拳对遗忘型轻度认知功能障碍患者认知功能影响的研究  

Study on Taijiquan in Patients with Amnestic Mild Cognitive Dysfunction

作　　者：包娜娜[1] 刘超[2] BAO Na-na;LIU Chao(Institute of Neurological Diseases,North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Neurology, Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China)

机构地区：[1]川北医学院神经疾病研究所,四川南充637000 [2]川北医学院附属医院神经内科,四川南充637000

出　　处：《医学信息》2019年第2期115-117,共3页Journal of Medical Information

摘　　要：目的探讨太极拳对遗忘型轻度认知功能障碍(a-MCI)患者认知功能的影响。方法将62例a-MCI患者随机分为对照组和观察组,每组31例。对照组患者接受常规健康教育,治疗组在此基础上接受太极拳干预治疗。两组患者分别在治疗前、治疗后6个月采用简明精神状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)以及事件相关电位P300对患者认知功能评价。结果对照组治疗前后MMSE、MoCA评分分别比较,差异无统计学意义(P>0.05);治疗后观察组MMSE、MoCA评分分别为(25.12±4.17)分、(25.64±3.19)分,均高于治疗前的(17.31±5.26)分、(20.13±2.48)分,且观察组MMSE、MoCA评分均高于对照组的(17.91±5.66)分、(19.93±2.68)分,差异具有统计学意义(P<0.05);对照组治疗前后P300潜伏期及波幅分别比较,差异无统计学意义(P>0.05);治疗后,观察组P300潜伏期较前缩短(363.12±36.97)ms vs(407.81±31.46)ms、波幅升高(6.64±4.59)μV vs(3.73±2.48)μV,差异有统计学意义(P<0.05),观察组P300潜伏期与波幅改变优于对照组的(403.61±32.26)ms和(3.73±2.38)μV,差异有统计学意义(P<0.05)。结论太极拳有助于改善a-MCI患者的认知功能,可作为一项干预措施用于防治a-MCI。Objective To investigate the effect of Taijiquan on cognitive function in patients with amnestic mild cognitive impairment(a-MCI).Methods 62 patients with a-MCI were randomly divided into control group and observation group,with 31 cases in each group.The patients in the control group received regular health education,and the treatment group received Taijiquan intervention on this basis.Patients in the two groups were evaluated for cognitive function using the Concise Mental Status Examination Scale(MMSE),the Montreal Cognitive Assessment Scale(MoCA),and the event-related potential P300 before and 6 months after treatment.Results There were no significant differences in MMSE and MoCA scores between the control group and the control group(P>0.05).After treatment,the MMSE and MoCA scores of the observation group were(25.12±4.17)and(25.64±3.19),respectively.The scores were higher than(17.31±5.26)and(20.13±2.48)before treatment,and the MMSE and MoCA scores of the observation group were higher than those of the control group(17.91±5.66)and(19.93±2.68),the difference was statistically significant(P<0.05).There was no significant difference in P300 latency and amplitude between the control group before and after treatment(P>0.05).After treatment,the P300 latency of the observation group was shorter than before(363.12±36.97)ms vs.(407.81±31.46)ms,amplitude increased(6.64±4.59)μV vs(3.73±2.48)μV,the difference was statistically significant(P<0.05).The latency and amplitude of P300 in the observation group were better than those in the control group(403.61±32.26)ms and(3.73±2.38)μV,the difference was statistically significant(P<0.05).Conclusion Taijiquan can improve the cognitive function of patients with a-MCI and can be used as an intervention to prevent a-MCI.

关 键 词：遗忘型轻度认知功能障碍 太极拳 事件相关电位 认知功能 

分 类 号：R749.16[医药卫生—神经病学与精神病学]