精芪升白汤联合FOLFOX6方案辅助化疗直肠癌的疗效观察  

Clinical observation of Jingqi Shengbai Decoction combined with neoadjuvant chemotherapy in the treatment of rectal cancer

作　　者：王淑萍[1] 郑秋惠[1] WANG Shuping;ZHEN Qiuhui(Department of Blood Oncology,Qinghai Traditional Chinese Medicine Hospital, Xining 810000,Qinhai,China)

机构地区：[1]青海省中医院血液肿瘤科,青海西宁810000

出　　处：《中南医学科学杂志》2019年第1期33-36,43,共5页Medical Science Journal of Central South China

摘　　要：观察精芪升白汤联合新辅助化疗治疗直肠癌的临床疗效及安全性。所选患者随机分为两组,对照组患者采用新辅助化疗FOLFOX6方案治疗,观察组采用精芪升白汤联合新辅助化疗FOLFOX6方案治疗。比较两组患者中医主要症候评分、肿瘤标志物水平、不良反应、生活质量评分及临床疗效。结果提示,观察组患者的肿瘤标志物水平、不良反应频次显著低于同期对照组;治疗后观察组的生活质量、中医主要症候评分及临床疗效明显优于对照组。结果说明,精芪升白汤联合新辅助化疗治疗直肠癌临床疗效显著,毒副作用少,值得在临床上推广。To observe the clinical efficacy and safety of Jingqi Shengbai decoction combined with neoadjuvant chemotherapy in the treatment of rectal cancer. The selected patients were randomly divided into two groups. The control group were treated with neo-adjuvant chemotherapy FOLFOX6, and the observation group was treated with Jingqi Shengbai Decoction and neoadjuvant chemotherapy FOLFOX6. The main symptom scores of TCM, tumor marker level, adverse reactions, quality of life and clinical efficacy of two groups of patients were compared. The level of tumor markers and the frequency of adverse reaction were significantly lower than those of control group. The quality of life, main symptom scores and clinical efficacy of TCM were superior to those of control group. Therefore, Jingqi Shengbai Decoction combined with neoadjuvant chemotherapy in the treatment of rectal cancer has significant clinical efficacy, less toxic side effects, and is worthy of clinical promotion.

关 键 词：精芪升白汤 直肠癌 新辅助化疗 生活质量 

分 类 号：R735.3[医药卫生—肿瘤]