全覆膜金属支架在慢性胰腺炎治疗中的应用研究  

Application of Fully Covered Metal Stent in the Treatment of Chronic Pancreatitis

作　　者：许哲[1] 王珍[1] 李焕祥 钟柳英 XU Zhe;WANGZhen;LI Huanxiang(The People’s Hospital of Dongguan City,Dongguan 523000,China)

机构地区：[1]广东省东莞市人民医院,广东东莞523000

出　　处：《中国医学创新》2019年第5期43-46,共4页Medical Innovation of China

基　　金：东莞市社会科技发展一般项目(201750715001277)

摘　　要：目的:探讨全覆膜金属支架在慢性胰腺炎(CP)治疗中的应用。方法:选取2014年1月-2018年1月本院CP患者60例,依据随机数字表法分为金属组和塑料组,每组30例。塑料组给予胰管内塑料支架植入术治疗,金属组给予胰管内全覆膜金属支架植入术治疗,比较两组手术疗效。结果:两组均全部成功完成支架置入,成功率为100%,差异无统计学意义(P>0.05)。金属组的住院时间、手术费用均少于塑料组,差异均有统计学意义(P<0.05)。术后4、24、72 h,两组的LIP、AMY均明显低于术前,差异均有统计学意义(P<0.05);但术后4、24、72 h,两组的血LIP、AMY比较,差异均无统计学意义(P>0.05)。6个月内,金属组急性胰腺炎、高淀粉酶血症发生率均明显低于塑料组,差异均有统计学意义(P<0.05)。6个月内,金属组支架并发症发生率明显低于塑料组,差异有统计学意义(P<0.05)。两组患者支架取出后胰管狭窄恢复情况比较,差异有统计学意义(P<0.05)。结论:全覆膜金属支架治疗CP的近期效果确切,且可有效减少患者术后急性胰腺炎、高淀粉酶血症及支架并发症发生,值得临床进一步推广。Objective:To discuss the application of fully covered metal stent in the treatment of chronic pancreatitis(CP).Method:100 patients with CP were selected from January 2014 to January 2018 in our hospital were selected,according to the random number table method,the patients were divided into metal group and plastic group,with 30 cases in each group.The plastic group was treated with plastic stent placement in the pancreatic duct.Metal group was treated with full stent placement in pancreatic duct.The operative effects of the two groups were compared.Result:Stent implantation was successfully completed in both groups,with a success rate of 100%,the difference was not statistically significant(P >0.05).The hospitalization time and operation cost of the metal group were less than those of the plastic group,the differences were statistically significant(P<0.05).4,24 and 72 h after surgery,LIP and AMY in both groups were significantly lower than those before surgery,the differences were statistically significant(P<0.05);however,4,24 and 72 h after surgery,LIP and AMY were compared between the two groups,the differences were not statistically significant(P >0.05).Within 6 months,the incidence of acute pancreatitis and hyperamylase in the metal group was significantly lower than that in the plastic group,with statistically significant difference(P<0.05).Within 6 months,the incidence of stent complications in the metal group was significantly lower than that in the plastic group,the difference was statistically significant(P<0.05).Conclusion:The short-term effect of CP treatment with fully coated metal stent is exact,and it can effectively reduce the incidence of postoperative acute pancreatitis,hyperamylasemia and stent complications in patients,which is worthy of further clinical promotion.

关 键 词：全覆膜金属支架 慢性胰腺炎 并发症 

分 类 号：R576[医药卫生—消化系统]