莫沙必利联合艾迪注射液对结直肠癌术后患者胃肠功能的改善研究  

Improvement Research of Mosapride Combined with Addie Injection on Gastrointestinal Function Post Colorectal Cancer Operation/

作　　者：余少康[1] 靳枫[1] 王树滨[1] 李柱[1] 潘毅贞 YU Shaokang;JIN Feng;WANG Shubin(Peking University Shenzhen Hospital,Shenzhen 518000,China)

机构地区：[1]北京大学深圳医院,广东深圳518000

出　　处：《中国医学创新》2019年第5期129-132,共4页Medical Innovation of China

摘　　要：目的:探讨莫沙必利联合艾迪注射液对结直肠癌术后患者胃肠功能的改善作用。方法:选取本院收治的结直肠癌术患者88例。按照随机数字表法将其分为对照组和观察组,各44例。两组均给予常规干预措施,对照组予莫沙必利口服治疗,观察组在对照组基础上给予艾迪注射液静脉滴注,两组连续干预12周。比较两组胃肠动力恢复情况、临床疗效、生活质量评分。结果:观察组排气、排便及肠鸣音恢复时间均显著短于对照组,比较差异均有统计学意义(P<0.01);观察组总有效率为93.18%,高于对照组的75.00%(P<0.05);治疗后,两组躯体功能、角色功能、认知功能、情绪功能及社会功能评分均高于治疗前,且观察组均高于对照组,比较差异均有统计学意义(P<0.01)。结论:莫沙必利联合艾迪注射液可促进结直肠癌术后患者胃肠功能的改善,提高临床疗效,改善患者生活质量。Objective:To investigate improvement role of Mosapride combined with Addie Injection on gastrointestinal function post colorectal cancer operation.Method:A total of 88 patients with colorectal cancer treated in our hospital were selected.According to the random number table method,they were divided into control group and observation group,44 cases in each group.They were given routine intervention measures,the control group was given oral Mosapride treatment,while observation group was given intravenous drip of Aidi Injection on the basis of control group.They were given continuous intervention for 12 weeks.The recovery of gastrointestinal motility,clinical efficacy and quality of life scores between two groups were compared.Result:The exhaust time,defecation time and recovery time of bowel sounds in observation group were significantly shorter than those of control group(P<0.01).The total effective rate was 93.18%in observation group,which was higher than 75.00%in control group(P<0.05).After treatment,the scores of physical function,role function,cognitive function,emotional function and social function of two groups were higher than those of before treatment,and observation group were higher than those of control group,the differences were statistically significant(P<0.01).Conclusion:Mosapride combined with Addie Injection can improve gastrointestinal function post colorectal cancer operation,increase the efficacy,and improve the quality.

关 键 词：莫沙必利 艾迪注射液 结直肠癌 胃肠功能 

分 类 号：R735.34[医药卫生—肿瘤]