柴胡疏肝汤合枸橼酸坦度螺酮治疗躯体化障碍的临床研究  

Clinical Research on Chaihu Shugan Decoction and Tandospirone Citrate in the Treatment of Somatization Disorder

作　　者：何乾超[1] 高玉广[1] 苏晗[1] 陈炜[1] 谭璐璐[1] HE Qianchao;GAO Yuguang;SU Han;CHEN Wei;TAN Lulu(The First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine,Nanning 530023,Guangxi,China)

机构地区：[1]广西中医药大学第一附属医院,南宁530023

出　　处：《中西医结合心脑血管病杂志》2019年第1期47-49,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广西壮族自治区中医药科技专项项目资助(No.GZPT13-10);广西壮族自治区临床重点专科建设项目经费资助

摘　　要：目的观察柴胡疏肝汤合枸橼酸坦度螺酮治疗躯体化障碍的临床疗效。方法将130例躯体化障碍病人随机分为两组,对照组运用枸橼酸坦度螺酮治疗,研究组运用柴胡疏肝汤合枸橼酸坦度螺酮治疗,疗程为4周。观察两组治疗前后症状自评量表(SCL-90)、汉密尔顿抑郁量表(HAMD)评分变化以及临床疗效。结果治疗4周后,研究组愈显率为69.23%,对照组愈显率为38.46%,研究组愈显率高于对照组(P <0.05)。治疗4周后,两组SCL-90各因子评分、HAMD评分均降低;且研究组SCL-90各因子评分、HAMD评分低于对照组(P <0.05)。结论柴胡疏肝汤合枸橼酸坦度螺酮治疗躯体化障碍优于单用枸橼酸坦度螺酮治疗。Objective To observe the effect of Chaihu Shugan decoction(CSD)and tandospirone citrate in the treatment of somatization disorder.Methods One hundred and thirty patients with somatization disorder were randomly divided into two groups:control group treated with tandospirone citrate,and treatment group treated with CSD and tandospirone citrate for 4 weeks.The Symptoms Checklist 90(SCL-90),Hamilton Depression Scale(HAMD)scores and clinical efficacy were observed before and after treatment.Results After 4 weeks of treatment,The total effective rate was significantly higher in treatment group than that in control group(69.23%vs 38.46%,P<0.05).The scores of SCL-90 and HAMD were decreased in two groups,which were lower in treatment group than those in the control group(P<0.05).Conclusion The effect of CSD and tandospirone citrate for the treatment of somatization disorder is superior to tanconate citrate alone.

关 键 词：躯体化障碍 柴胡疏肝汤 枸橼酸坦度螺酮 汉密尔顿抑郁量表 症状自评量表 

分 类 号：R741[医药卫生—神经病学与精神病学] R289.5[医药卫生—临床医学]