富血小板纤维蛋白膜在位点保存应用中对牙龈组织愈合、骨量保存的影响分析  

Effects Analyze of Platelet-Rich Fibrin Membrane on Gingival Tissue Healing and Bone Mass Preservation in the Application of Site Preservation

作　　者：赵西博 王国庆 石磊 郝志红[1] 刘会娟 刘焕磊 ZHAO Xi-bo;WANG Guo-qing;SHI Lei;AN Zhihong;LIU Hui-juan;LIU Huan-lei(Planting Section,Anyang No.6 People’s Hospital,Henan Province,455000,China)

机构地区：[1]安阳市第六人民医院种植科,河南安阳455000

出　　处：《中国医疗美容》2019年第1期73-77,共5页China Medical Cosmetology

摘　　要：目的将富血小板纤维蛋白膜(PRF)用于引导骨组织再生位点保存术中,分析其对牙龈组织愈合、骨量保存的影响。方法选取拔牙后行骨组织再生位点保存术的患者66例,随机分为两组,试验组33例,Bio-Oss植骨材料表面覆盖PRF膜,对照组在Bio-Oss植骨材料表面覆盖Bio-Gide膜,比较术后1W、术后2W各时段创面愈合率,通过CBCT比较术前、术后3个月牙槽骨唇腭向高度及厚度。结果试验组创面愈合时间与对照组相比,相对更短(P <0.05);试验组术后1W、术后2W各时段创面愈合率与对照组相比,均相对更高(P <0.05);两组拔牙前牙槽骨高度、宽度相比,差异均不明显(P> 0.05),两组术后3个月牙槽骨高度、宽度均有所丢失,但试验组槽骨高度、宽度与对照组相比,均相对更高/宽(P <0.05)。结论富血小板纤维蛋白膜用于骨组织再生位点保存术中效果显著,可促进牙龈组织快速愈合,减少骨量丢失,促进新生骨生成,为种植牙奠定良好基础,值得临床应用。Objective Platelet-rich fibrin membrane(PRF)was used to guide bone tissue regeneration site preservation,and its effects on gingival tissue healing and bone mass preservation were analyzed.Methods 66 patients who underwent bone tissue regeneration site preservation after tooth extraction were randomly divided into two groups.The experimental group consisted of 33 patients and the Bio-Oss bone graft material was covered the PRF membrane,and the control group was covered the Bio-Gide membrane,the wound healing rate was compared between 1W and 2W after operation.The height and thickness of alveolar bone lip line were compared postoperative 3 months by CBCT Results The wound healing time of the experimental group was shorter than that of the control group(P<0.05);The wound healing rate of the experimental group at 1W and 2W after surgery was higher than that of the control group(P<0.05);There was no significant difference in the height and width of the alveolar bone between the two groups before tooth extraction(P >0.05)The height and width of the alveolar bone between the two groups were partially lost 3 months after surgery,but the height and width of the alveolar bone in the experimental group were higher/wider than those in the control group(P<0.05).Conclusion Platelet-rich fibrin membrane has a significant effect on the bone tissue regeneration site preservation,which can promote the rapid healing of gingival tissue,reduce bone loss,promote the generation of new bone,and lay a good foundation for the implant tooth,which is worthy of clinical application.

关 键 词：富血小板纤维蛋白膜 牙龈组织愈合 GBR术 骨量保存 

分 类 号：R783.6[医药卫生—口腔医学]