牙种植体周围微生物研究  

A review of peri-implant microbiology

作　　者：程磊[1] 于海洋[2] 吴尧[3] 包崇云[4] 杨帮成[3] 满毅[5] 孙瑶 岩晓丽 周学东[1] Cheng Lei;Yu Haiyang;Wu Yao;Bao Chongyun;Yang Bangcheng;Man Yi;Sun Yao;Yan Xiaoli;Zhou Xuedong(State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Dept.of Cariology and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Dept.of Prosthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;Engineering Research Center in Biomaterials,Sichuan University&Sichuan Guojia Biomaterials Engineering Technology Limited Company,Chengdu 610064,China;State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Dept.of Implant,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;Dept.of Implant,The Affiliated Stomatology Hospital of Tongji University,Shanghai Engineering Research Center of Tooth Restoration and Regeneration,Shanghai 200072,China;Chengdu Puchuan Biomaterials Corporation,Ltd,Chengdu 611731,China)

机构地区：[1]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院牙体牙髓病科,成都610041 [2]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院修复科,成都610041 [3]四川大学生物材料工程研究中心四川国佳生物医学材料工程技术有限公司,成都610064 [4]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院,成都610041 [5]口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院种植科,成都610041 [6]同济大学口腔医学院.附属口腔医院种植科上海牙组织修复与再生工程技术研究中心,上海200072 [7]成都普川生物医用材料股份有限公司,成都611731

出　　处：《华西口腔医学杂志》2019年第1期7-12,共6页West China Journal of Stomatology

基　　金：国家重点研发计划(2016YFC1102701)~~

摘　　要：牙种植术是目前修复牙列缺损和牙列缺失的主要治疗方案,但是种植体周围微生态失衡易造成种植体周围疾病的发生,进而导致种植失败。从20世纪80年代开始,种植体周围微生物的研究就成为了口腔微生物研究的热点之一。正常种植体周围微生物和种植体周围炎症相关微生物存在着差异,这些差异直接或间接增加了种植体周围疾病的风险,因此寻找种植体周围黏膜炎和种植体周围炎"核心微生物组"是目前研究的关键。Dental implants represent the majority of treatment strategies used to replace missing teeth.However,peri-implant diseases caused by disturbance in peri-implant microbiological balance are among the reasons for implant failure.Since the 1980s,peri-implant microorganisms have been a hot research topic in dental microbiology.The bacterial ecology between the disease and health largely differs,which directly or indirectly increases the risk of peri-implant diseases.Accordingly,the determination of the‘core microbiome’of peri-implantitis and peri-implant mucositis is a key point of recent research.

关 键 词：种植体 微生物 种植体周围黏膜炎 种植体周围炎 核心微生物组 

分 类 号：R780.2[医药卫生—口腔医学]