食用酸汤与贵州燃煤型氟中毒关系的研究  

Study on relationship between edible sour soup and coal-burning fluorosis

作　　者：刘俊[1,2] 罗明江 赵训 杨胜 张元梅 周迪 LIU Jun;LUO Mingjiang;ZHAO Xun;YANG Sheng;ZHANG Yuanmei;ZHOU Di(Preventive Medicine Experimental Teaching Center,School of Public Health,Zunyi MedicalUniversity,Zunyi,Guizhou 563003,China;Experimental Teaching Demonstration Center forPreventive Medicine of Guizhou Province,Zunyi,Guizhou 563003,China;Department of Infection,Zunyi Municipal Fourth People′s Hospital,Zunyi,Guizhou 563003,China;Department of Chronic Disease Prevention and Treatment,Zhijin CountyCenter for Disease Control and Prevention,Zhijin,Guizhou 552100,China)

机构地区：[1]遵义医学院预防医学实验教学中心,贵州遵义563006 [2]贵州省预防医学实验教学示范中心,贵州遵义563006 [3]贵州省遵义市第四人民医院院感科,563003 [4]贵州省织金县疾病预防控制中心慢性病防治科,552100

出　　处：《重庆医学》2019年第4期649-653,共5页Chongqing medicine

基　　金：国家自然科学基金资助项目(81460497);遵义医学院博士启动基金(F706)

摘　　要：目的探讨贵州地区特色食品酸汤与燃煤型氟中毒的关系。方法采用横断面研究,在贵州省织金县招募1 101人进行面对面的问卷调查,调查内容包括一般人口学资料、生活习惯、氟中毒相关因素及膳食调查。结果经多因素分析发现干辣椒、玉米及炉灶烘烤食物是燃煤型氟中毒的危险因素(P<0.05)。进一步根据酸汤食用量进行四等分分组,发现酸汤食用量越大,燃煤型氟中毒风险越低(P<0.01)。酸汤食用量最大组燃煤型氟中毒风险明显低于酸汤食用量最小组(P<0.01),OR95%可信区间为0.22(0.12～0.39)。将氟中毒分为氟斑牙和氟骨症进行敏感性分析,结果与氟中毒结果一致。结论食用酸汤是燃煤型氟中毒的独立保护因素。Objective To investigate the relationship between edible sour soup and coal-burning fluorosis. Methods The cross-sectional study was conducted.A total of 1 101 participants were recruited in Zhijin County and performed the face-to-face questionnaire investigation.The investigation contents included the general demographic condition,living habits,fluorosis related factors and dietary survey. Results The multivariate analysis found that the dried chilli,corn and roasting food by coal were the risk factors of coal-burning fluorosis.The sour soup consumptions were further divided into the four groups by quartile.It was found that the greater the sour soup consumption,the lower the coal-burning fluorosis( P <0.01).The coal-burning fluorosis risk in the maximal edible sour soup consumption group was significantly lower than that in the minimal edible sour soup group[ P <0.01,95% confidence interval( CI ) 0.22 (0.12-0.39)].The sensitivity was analyzed by dividing fluorosis into dental fluorosis and skeletal fluorosis,the analytical results were consistent with the fluorosis results. Conclusion Sour soup is a dependent protective factor for the coal burning fluorosis.

关 键 词：横断面研究 酸汤 燃煤型氟中毒 影响因素 

分 类 号：R599.1[医药卫生—内科学]