磁共振ASL及DWI成像在急性缺血性脑卒中患者中的应用  

Application of Magnetic Resonance ASL and DW Imaging in Patients with Acute Cerebral Ischemic Stroke

作　　者：梁慧[1] LIANG Hui(Department of Neurology,the Second Hospital of Jiaozuo City,Jiaozuo 454000,Henan Province,China)

机构地区：[1]河南省焦作市第二人民医院神经内科,河南焦作454000

出　　处：《中国CT和MRI杂志》2019年第1期34-36,共3页Chinese Journal of CT and MRI

摘　　要：目的观察磁共振动脉自旋标记(3D-ASL)及磁共振弥散加权成像(DWI)在急性缺血性脑卒中(CIS)患者中的临床应用。方法选取2017年1月-2018年4月我院诊治的CIS患者共60例,另纳入30名健康志愿者作为对照组,均进行3D-ASL及DWI扫描,对比两种检查方式在CIS患者中的应用价值。结果诊断为右侧大脑半球急性缺血性脑卒中患者共34例,表现为右侧脑血流量(CBF)绝对值显著低于左侧,两侧CBF绝对值均低于健康对照组,均有统计学意义(P<0.05);诊断为左侧大脑半球急性缺血性脑卒中患者共26例,表现为两侧脑血流量(CBF)绝对值均低于健康对照组,均有统计学意义(P<0.05)。结论3D-ASL能够清楚显示CIS患者局部脑组织缺血梗死病灶的血流动力学改变,结合CBF值能更为客观的反应脑组织缺血梗死灌注情况,为CIS的临床诊断提供重要依据。Objective To observe the clinical application of magnetic resonance arterial spin labeling(3D-ASL)and diffusion weighted imaging(DWI)in patients with acute cerebral ischemic stroke(CIS).Methods A total of 60 cases of CIS patients in our hospital from January 2017 to February 2018 were selected,and 30 healthy volunteers were enrolled as control group,and all of them were given 3D-ASL and DWI imaging scans respectively.The application value of the two methods in CIS patients was compared.Results In 34patients with acute ischemic stroke on the right side,the absolute value of right cerebral blood flow(CBF)was significantly lower than that of the left side,and the absolute values of CBF on both sides were lower than those in healthy control group(P<0.05).In 26patients with acute ischemic stroke on the left side,the absolute values of bilateral cerebral blood flow(CBF)were lower than those in healthy control group(P<0.05).Conclusion3D-ASL can clearly show the hemodynamic changes of ischemic infarct lesions in patients with CIS,and combined with CBF value was more objective in responding to the ischemic infarction perfusion of brain tissue,and can provide an important basis for the clinical diagnosis of CIS.

关 键 词：动脉自旋标记 磁共振弥散加权成像 急性缺血性脑卒中 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]