二次复发性膀胱癌术中放疗的远期临床观察  

Long-term Clinical Observation on Intraoperative Radiotherapy for Secondary Recurrent Bladder Cancer

作　　者：腾鹏[1] 郭汝明[1] 王彤[1] 张梦妍 韩周宏 TENG Peng;GUO Ruming;WANG Tong;ZHANG Mengyan;HAN Zhouhong(Department of Second Surgery Urology,Qiqihar First Hospital,Qiqihar Heilongjiang 161005,China)

机构地区：[1]齐齐哈尔市第一医院泌尿外二科,黑龙江齐齐哈尔161005

出　　处：《中国卫生标准管理》2019年第2期62-64,共3页China Health Standard Management

基　　金：黑龙江省齐齐哈尔市科学技术计划指导项目(名称:二次复发性膀胱癌术中放疗的远期临床观察编号:SFZD-2017061)

摘　　要：目的探讨分析二次复发性膀胱癌术中放疗的远期临床观察,为提供更好的治疗方案打下基础。方法选择我院自2012年1月—2013年12月收治的二次复发膀胱癌手术患者71例为研究对象,根据患者就诊的先后将患者分为A、B、C三组各40、18、13例,A组使用术中放疗+膀胱部分切除组+术后吉西他滨膀胱灌注化疗;B组使用膀胱部分切除+术后吉西他滨膀胱灌注化疗;C组膀胱根治性切除组;对比患者的临床治疗效果。结果治疗效果对比,A、B两组的数据与C组的数据进行对比差异存在统计学意义,患者术后的生存质量、二次复发术后5年生存率A组患者均要优于B组、C组的患者。结论膀胱癌术中放疗的治疗方案具有定位精确,副损伤少等优点,治疗效果优于传统的膀胱部分切除术和根治性全膀胱切除术。Objective To investigate the long-term clinical observation of intraoperative radiotherapy for secondary recurrent bladder cancer.Methods From January 2012 to December 2013,71 patients with secondary recurrence of bladder cancer were selected as the study subjects.According to the patient's order,the patients were divided into three groups:A,B and C,40,18 and 13 cases respectively.Group A received intraoperative radiotherapy,partial cystectomy and postoperative gemcitabine intravesical infusion chemotherapy.Group B was treated with gemcitabine intravesical chemotherapy after partial cystectomy and group C with radical cystectomy.Results The data of group A and group B in group A and group B were significantly different from those in group C.The survival quality of patients after operation and 5-year survival rate after secondary recurrence were better than those in group B and group C.Conclusion Intraoperative radiotherapy for bladder cancer has advantages of precise location and less side injury and it is better than traditional partial cystectomy and radical total cystectomy.

关 键 词：二次复发性膀胱癌 术中放疗 膀胱部分切除 术后放疗 远期观察 临床效果 

分 类 号：R737[医药卫生—肿瘤]