晚期食管癌同步放化疗、序贯性放化疗对比  

Comparison of the Effects of Concurrent Chemoradiotherapy and Sequential Chemoradiotherapy in Advanced Esophageal Cancer

作　　者：孙丽立 王乐乐[1] 尹胜杰[1] 季洪波[1] SUN Lili;WANG Lele;YIN Shengjie;JI Hongbo(Department of First Internal Medicine in Oncology,Chifeng Hospital,Chifeng Inner Mongolia 024000,China)

机构地区：[1]赤峰市医院肿瘤内一科,内蒙古赤峰024000

出　　处：《中国卫生标准管理》2019年第2期69-71,共3页China Health Standard Management

摘　　要：目的探讨同步放化疗、序贯性放化疗在晚期食管癌治疗中的临床效果。方法选取2014年2月—2017年2月收治的98例晚期食管癌患者作研究对象,按放化疗方案不同予以分组:同步组(n=49)采取同步放化疗方案,序贯组(n=49)采取序贯性放化疗方案,对比近期疗效以及副反应的差异。结果同步组的近期治疗有效率高于序贯组(P <0.05),且副反应发生率高于序贯组(P <0.05)。结论同步放化疗在晚期食管癌治疗中的近期疗效优于序贯性放化疗,虽会增加副反应,但患者可耐受。Objective To investigate the clinical effect of concurrent radiotherapy and sequential radiotherapy and chemotherapy in the treatment of advanced esophageal cancer.Methods Ninety-eight patients with advanced esophageal cancer admitted from February 2014 to February 2017 were selected as the study subjects.They were grouped according to different radiotherapy and chemotherapy schemes:synchronous group(n=49)adopted synchronous radiotherapy and chemotherapy scheme,and sequential group(n=49)adopted sequential radiotherapy and chemotherapy scheme.The short-term efficacy and side effects were compared.Results The short-term effective rate of synchronous group was higher than that of sequential group(P<0.05),and the incidence of side effects was higher than that of sequential group(P<0.05).Conclusion The short-term efficacy of concurrent chemoradiotherapy in the treatment of advanced esophageal cancer is better than that of sequential chemoradiotherapy.Although it can increase side effects,it is tolerable for patients.

关 键 词：同步放化疗 序贯性放化疗 副反应 晚期 食管癌 生存率 

分 类 号：R735[医药卫生—肿瘤]